Exploring the effects of positive airway pressure on sudden hearing loss and sleep apnea

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the impact of positive airway pressure (PAP) therapy on patients diagnosed with idiopathic sudden sensorineural hearing loss (ISSHL) who also have obstructive sleep apnea (OSA). Conducted at Beijing Tsinghua Changgung Hospital, the study will enroll participants aged 18 to 70 who meet specific diagnostic criteria for both conditions. The trial will utilize a randomized controlled design to assess the effectiveness of PAP alongside other treatments like Methylprednisolone Hemisuccinate and Ginaton over a period extending from December 2019 to December 2029.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. aged \>= 18 and \<= 70,
2. diagnosed with OSA by full-night in-lab or home-stay PSG according to AASM 2012 criteria, and AHI \> 15/h,
3. diagnosed with ISSHL by AAO-HNS 2019 criteria,
4. ISSHL onset within 1 week.

Exclusion Criteria:

1. sudden hearing loss with certain causes,
2. with severe comorbid diseases,
3. pregnant or breast-feeding women,
4. AHI \<= 15/h,
5. hearing threshold recovered \> 50% when included,
6. previously regularly treated with PAP.

Where it's running

• Beijing Tsinhgua Changgung Hospital
  Beijing, Beijing Municipality, China Recruiting

Study contacts

• Principal investigator: Juanjuan Gao, MD — Beijing Tsinghua Changung Hospital
• Study coordinator: Jingying Ye, MD
• Email: yejingying@163.vip.com
• Phone: +86-13701396970

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.