Exploring the connection between epilepsy and psychotic disorders

Study of Association Between Ictal Affective Symptoms, Ictal Consciousness Level and the Presence of Comorbid Epileptic Psychoses

Observational Central Hospital, Nancy, France · NCT06960811

This study is trying to see if certain emotional symptoms during seizures in people with epilepsy are linked to a higher chance of developing psychotic disorders.

Quick facts

Study typeObservational
Enrollment120 (estimated)
Ages18 Years and up
SexAll
SponsorCentral Hospital, Nancy, France Academic / other
Locations1 site (Nancy, Lorraine)
Trial IDNCT06960811 on ClinicalTrials.gov

What this trial studies

This observational study aims to investigate the relationship between epileptic symptoms and the occurrence of psychotic disorders in patients with epilepsy. It focuses on understanding whether specific emotional symptoms during seizures are linked to a higher risk of developing psychosis. The study will involve patients who have been hospitalized for video-EEG recording and have undergone a psychiatric evaluation. By comparing patients with and without psychotic comorbidities, the research seeks to shed light on the often-overlooked psychiatric aspects of epilepsy.

Who should consider this trial

Good fit: Ideal candidates for this study are adults with a confirmed diagnosis of epilepsy who have been hospitalized for video-EEG monitoring.

Not a fit: Patients who do not have recorded seizures during the video-EEG will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved diagnosis and treatment strategies for patients with epilepsy and associated psychotic disorders.

How similar studies have performed: While the specific approach of this study is novel, there is a growing body of literature indicating the importance of understanding psychiatric comorbidities in epilepsy.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with a confirmed diagnosis of epilepsy
* Patients hospitalized for at least 5 days for a video-EEG recording
* Patients with a psychiatric evaluation, conducted between 01/01/2016 and 04/01/2025.
* Adult patients able to express their opposition to the use of their data.

Exclusion Criteria:

* Absence of seizure recorded during the video-EEG

Where this trial is running

Nancy, Lorraine

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Epilepsy With Partial Onset Seizures With or Without Secondary GeneralizationPsychosesEpilepsy, Generalizedpsychoses of epilepsypostictal psychosisinterictal psychosisepilepsyclinical research
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.