Exploring the causes of fungal ear infections

Exploring the Risk Factors of Otomycosis: A Case-Control Study

Observational Zhongshan Hospital Xiamen University · NCT06530069

This study looks at what might cause fungal ear infections by comparing people who have symptoms with those who are healthy to see if certain behaviors or exposures make a difference.

Quick facts

Study typeObservational
Enrollment200 (estimated)
SexAll
SponsorZhongshan Hospital Xiamen University Academic / other
Locations1 site (Xiamen, Fujian)
Trial IDNCT06530069 on ClinicalTrials.gov

What this trial studies

This observational study aims to identify the risk factors associated with otomycosis, a type of fungal ear infection. Participants will be divided into two groups: those with symptoms of fungal otitis externa and a healthy control group. Through detailed questionnaire surveys, researchers will compare behaviors and exposures between the two groups to determine what factors may contribute to the development of this condition.

Who should consider this trial

Good fit: Ideal candidates include individuals experiencing symptoms of fungal otitis externa, such as ear pain, itching, and discharge.

Not a fit: Patients with conditions like otitis media or tympanic membrane perforation may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could help identify preventable risk factors for otomycosis, leading to better management and prevention strategies for patients.

How similar studies have performed: While there may be studies on otomycosis, this specific observational approach focusing on risk factors is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Symptoms in the case group include tinnitus, ear fullness or blockage, itching, ear pain, discharge, and hearing loss. Physical examination reveals the presence of hyphae, scabs, secretions, masses, pus, red skin, erosion, swelling, or granulation in the ear canal. Laboratory fungal cultures must be positive. The control group does not have the aforementioned ear symptoms and has not sought medical attention for ear-related symptoms.

Exclusion Criteria:

* Patients with otitis media, tympanic membrane perforation, or post-radiotherapy.

Where this trial is running

Xiamen, Fujian

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Otomycosispredisposing factor
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.