Exploring survival and gene mutations in lung cancer staging

Survival Validation and Gene Mutations of N Descriptors in the Ninth Edition of the TNM Classification for Lung Cancer

Fudan University · NCT06349252

This study looks at how certain gene changes and survival rates in lung cancer patients with specific disease stages can help doctors understand and improve treatment outcomes after surgery.

Quick facts

Study typeObservational
Enrollment1263 (estimated)
SexAll
SponsorFudan University (other)
Drugs / interventionschemotherapy
Locations1 site (Shanghai, Shanghai)
Trial IDNCT06349252 on ClinicalTrials.gov

What this trial studies

This observational study investigates the survival outcomes and gene mutations associated with the N descriptors in the ninth edition of the TNM classification system for non-small cell lung cancer. It focuses on patients with pathological N2 status and examines how these factors correlate with stage grouping and overall survival. The study involves radical resection as the primary intervention to assess the impact of the new classification on patient outcomes.

Who should consider this trial

Good fit: Ideal candidates for this study are patients diagnosed with non-small cell lung cancer who have pathological N2 status.

Not a fit: Patients undergoing neoadjuvant chemotherapy will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance the understanding of lung cancer staging and improve treatment strategies for patients with non-small cell lung cancer.

How similar studies have performed: While this study explores a new classification system, similar studies have previously shown the importance of staging in predicting outcomes in lung cancer.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

Pathological N2.

Exclusion Criteria:

Patients undergoing neoadjuvant chemotherapy

Where this trial is running

Shanghai, Shanghai

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Non-small Cell Lung Cancer

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.