Exploring sensory modulation dysfunction's role in PTSD

Sensory Modulation Dysfunction as a Risk Factor for Posttraumatic Stress Disorder - A Randomized Control Trial

Not applicable Interventional Tel Aviv University · NCT05967962

This study is trying to see if problems with how people process sensory information can affect the development of PTSD and its symptoms in young adults who have experienced combat trauma.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment100 (estimated)
Ages18 Years to 28 Years
SexAll
SponsorTel Aviv University Academic / other
Locations1 site (Tel Aviv)
Trial IDNCT05967962 on ClinicalTrials.gov

What this trial studies

This study investigates how sensory modulation dysfunction (SMD) may influence the development of posttraumatic stress disorder (PTSD) and its associated symptoms, including chronic pain and cognitive impairments, following exposure to combat trauma. It employs a single-blind randomized control design with 100 participants aged 18 to 28, who will be divided into groups to watch either traumatic or non-traumatic films. Assessments will occur at four time points to evaluate the impact of sensory processing on PTSD symptomatology and executive function. The study aims to fill a gap in current PTSD research by focusing on the sensory domain.

Who should consider this trial

Good fit: Ideal candidates are healthy individuals aged 18 to 28, with or without sensory modulation dysfunction.

Not a fit: Patients with neurological, psychiatric, or neurodevelopmental disorders, as well as those with chronic pain or substance use disorders, may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved understanding and treatment strategies for individuals with PTSD and sensory processing issues.

How similar studies have performed: While the specific focus on sensory modulation dysfunction in PTSD is relatively novel, related studies have shown promising results in understanding sensory processing's impact on trauma-related conditions.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Intact or corrected vision
* Proficiency in Hebrew
* Exclusion Criteria:
* Neurological disorders
* Psychiatric disorders
* Neurodevelopmental disorders
* Substance use disorder
* Chronic pain
* Regular intake of medications.
* Cultural and societal backgrounds that might bias participant reaction to study protocol (i.e., nationality)

Where this trial is running

Tel Aviv

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Posttraumatic Stress DisorderSensory Processing Disordersensory processingexecutive functiontraumaperitrauma
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.