Exploring selenoproteins in breast cancer prognosis and treatment.

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This multicentric observational study investigates the role of selenoproteins as prognostic markers and potential therapeutic targets in breast cancer, specifically triple-negative breast cancer (TNBC). The study includes both retrospective and prospective components, where tissue microarrays will be prepared from surgical samples of TNBC patients, and plasma samples from healthy subjects and metastatic TNBC patients will be analyzed for selenoprotein expression using ELISA. The aim is to better understand the relationship between selenoproteins and breast cancer outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* TNBC breast cancer patients, before any drug treatment
* healthy women aged 25-60

Exclusion Criteria:

* donors suffering from diabetes, hypertension, active infectious states, HIV infection, Hepatitis B or C, chronic inflammatory diseases, current or previous neoplasms, heart disease or drug treatment.

Where it's running

• Istituto Nazionale Tumori - Fondazione "G.Pascale", IRCCS
  Naples, Napoli, Italy Recruiting
• Istituto Nazionale Tumori Regina Elena
  Roma, Roma, Italy Recruiting

Study contacts

• Principal investigator: Alfredo Budillon, M.D. — IRCCS I.N.T. "G. Pascale"
• Study coordinator: Elena Di Gennaro, PhD
• Email: e.digennaro@istitutotumori.na.it
• Phone: 08117770584

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.