Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Exploring RPSA as a biomarker for pancreatic cancer prognosis

Official title: RPSA as a Potential Prognostic Biomarker of PDAC

Run by CHU de Reims · NCT04575363 · Data updated 2026-11-12

This study is testing if a protein found in blood can help predict how pancreatic cancer will progress in patients who have had surgery or chemotherapy.

More Pancreatic Ductal Adenocarcinoma (PDAC) trials

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment90 (estimated)
SponsorCHU de Reims
Academic / other
Drugs / interventionschemotherapy
Locations1 site (Reims)
StatusRecruiting
StartedOctober 18, 2021
Main results expectedOctober 18, 2026
Study endsOctober 18, 2027
Registry record updatedNovember 9, 2023
Trial IDNCT04575363 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include adults over 18 years old with a diagnosis of resectable or potentially resectable pancreatic tumors being treated at Reims University Hospital.

Probably not a fit

Patients with a prior history of cancer or those diagnosed with conditions other than PDAC may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the role of ribosomal protein SA (RPSA) as a potential prognostic biomarker for pancreatic ductal adenocarcinoma (PDAC). It aims to analyze blood samples from patients treated at Reims University Hospital for resectable or potentially resectable pancreatic tumors, with or without prior chemotherapy. The study seeks to determine if RPSA expression correlates with tumor invasion and metastatic potential, addressing the current lack of effective biomarkers for PDAC prognosis.

Why it matters

Potential benefit: If successful, this study could lead to improved prognostic assessments for patients with pancreatic cancer, enabling more personalized treatment strategies.

How similar studies have gone: While the exploration of RPSA as a biomarker is relatively novel, similar studies have shown promise in identifying biomarkers for other cancers, suggesting potential for success.

Who can join: the full rules

Show full inclusion / exclusion criteria
inclusion criteria :

* Patients treated at the Reims University Hospital for a resectable or potentially resectable pancreatic tumor, with or without neoadjuvant chemotherapy
* Adults (aged more than 18 years old)
* Patients who have signed the informed consent form

exclusion criteria :

* Patients with a prior history of cancer (excluding basal cell carcinoma or in situ cervical cancer that received conventional cancer treatment).
* Minors
* Patients for whom PDAC is not the retained diagnosis

Where it's running

  • Damien JOLLY
    Reims, France
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.