Exploring RPSA as a biomarker for pancreatic cancer prognosis
Official title: RPSA as a Potential Prognostic Biomarker of PDAC
Run by CHU de Reims · NCT04575363 · Data updated 2026-11-12
This study is testing if a protein found in blood can help predict how pancreatic cancer will progress in patients who have had surgery or chemotherapy.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 90 (estimated) |
| Sponsor | CHU de Reims Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Reims) |
| Status | Recruiting |
| Started | October 18, 2021 |
| Main results expected | October 18, 2026 |
| Study ends | October 18, 2027 |
| Registry record updated | November 9, 2023 |
| Trial ID | NCT04575363 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults over 18 years old with a diagnosis of resectable or potentially resectable pancreatic tumors being treated at Reims University Hospital.
✕Probably not a fit
Patients with a prior history of cancer or those diagnosed with conditions other than PDAC may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the role of ribosomal protein SA (RPSA) as a potential prognostic biomarker for pancreatic ductal adenocarcinoma (PDAC). It aims to analyze blood samples from patients treated at Reims University Hospital for resectable or potentially resectable pancreatic tumors, with or without prior chemotherapy. The study seeks to determine if RPSA expression correlates with tumor invasion and metastatic potential, addressing the current lack of effective biomarkers for PDAC prognosis.
Why it matters
Potential benefit: If successful, this study could lead to improved prognostic assessments for patients with pancreatic cancer, enabling more personalized treatment strategies.
How similar studies have gone: While the exploration of RPSA as a biomarker is relatively novel, similar studies have shown promise in identifying biomarkers for other cancers, suggesting potential for success.
Who can join: the full rules
Show full inclusion / exclusion criteria
inclusion criteria : * Patients treated at the Reims University Hospital for a resectable or potentially resectable pancreatic tumor, with or without neoadjuvant chemotherapy * Adults (aged more than 18 years old) * Patients who have signed the informed consent form exclusion criteria : * Patients with a prior history of cancer (excluding basal cell carcinoma or in situ cervical cancer that received conventional cancer treatment). * Minors * Patients for whom PDAC is not the retained diagnosis
Where it's running
-
Damien JOLLY
Reims, France Recruiting
Study contacts
- Study coordinator: Jean-Baptiste OUDART
- Email: joudart@chu-reims.fr
- Phone: 03 10 73 62 87
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.