Exploring Pain Descriptors in Ankylosing Spondylitis

Descriptors of Neuropathic Spinal Pain and Their Relations With Functional Status in Ankylosing Spondylitis Patients

Observational Bozyaka Training and Research Hospital · NCT05096767

This study is trying to understand the different types of pain people with ankylosing spondylitis feel in their spine to see how it affects their daily life.

Quick facts

Study typeObservational
Enrollment130 (estimated)
Ages18 Years to 70 Years
SexAll
SponsorBozyaka Training and Research Hospital Academic / other
Locations1 site (Izmir)
Trial IDNCT05096767 on ClinicalTrials.gov

What this trial studies

This observational study aims to investigate the neuropathic pain descriptors associated with spinal pain in patients diagnosed with ankylosing spondylitis (AS). By conducting a prospective, cross-sectional analysis, the researchers will compare sensory descriptors between patients experiencing neuropathic pain and those without. The study seeks to enhance understanding of how these descriptors relate to functional status in AS patients, filling a gap in existing literature regarding inflammatory spinal pain. Participants will complete questionnaires and inventories to provide data for this analysis.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals diagnosed with ankylosing spondylitis who report moderate to severe spinal pain.

Not a fit: Patients with conditions such as diabetes, fibromyalgia, or recent treatments that may cause neuropathy are unlikely to benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies for patients with ankylosing spondylitis.

How similar studies have performed: While there has been limited research on sensory descriptors in AS, previous studies on neuropathic pain in other conditions suggest potential for meaningful insights.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Being diagnosed with AS according to the Modified NewYork Criteria
* Visual Analogue Scale spinal pain score ≥ 3

Exclusion Criteria:

1. Diabetes mellitus, renal insufficiency, hypothyroidism
2. Postherpetic neuralgia, spinal cord compression
3. Being diagnosed as fibromyalgia in the last month or widespread pain indicating fibromyalgia
4. Malignancy
5. Pregnancy
6. Severe cardiac disease
7. In the last three months medical treatment leading to neuropathy (colchicine etc.)
8. In the last three months drug use for the treatment of fibromyalgia, depression or anxiety

Where this trial is running

Izmir

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Ankylosing Spondylitis
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.