Exploring non-medication options for managing chronic pain in Veterans

Options for Pain Management Using Nonpharmacological Strategies (OPTIONS)

Not applicable Interventional VA Office of Research and Development · NCT05563792

This study is testing different non-medication methods, like therapy and exercise, to help Veterans manage their chronic pain without relying on drugs.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment296 (estimated)
Ages18 Years and up
SexAll
SponsorVA Office of Research and Development Federal
Locations1 site (Indianapolis, Indiana)
Trial IDNCT05563792 on ClinicalTrials.gov

What this trial studies

This study aims to assist Veterans in managing chronic pain through non-pharmacological strategies rather than medications. Participants will work with a coach to identify their personal values and goals, and explore various non-medication approaches that align with these. The study emphasizes the use of evidence-based treatments such as cognitive behavioral therapy, exercise, acupuncture, and yoga, which are widely available within the Veterans Health Administration. The initiative is part of a broader effort to reduce reliance on opioids and promote multimodal pain management strategies.

Who should consider this trial

Good fit: Ideal candidates are Veterans experiencing musculoskeletal pain in the low back, cervical spine, or extremities for at least three months, with moderate pain intensity and a willingness to try new treatments.

Not a fit: Patients with severe medical conditions, long-term opioid therapy, or significant cognitive impairment may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could provide Veterans with effective pain management alternatives that improve their quality of life without the risks associated with opioid use.

How similar studies have performed: Other studies have shown success with similar non-pharmacological approaches to pain management, indicating a promising direction for treatment.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* have musculoskeletal pain in the low back, cervical spine, or extremities (hip, knee, or shoulder) for at least 3 months,
* have at least moderate pain intensity and interference with function, defined by a score of 4 (possible range: 0-10) on the PEG, a 3-item measure of pain intensity, interference with enjoyment of life, and interference with general activity (obtained from phone screener),
* have a primary care appointment scheduled or due in approximately the next three months.
* open to trying new pain treatments

Exclusion Criteria:

* a psychiatric hospitalization in the past 6 months,
* long-term opioid therapy
* severe medical conditions likely precluding participation (e.g., NY Heart Association Class III or IV heart failure) which includes heart attack, stroke, and cancer, or
* if the eligibility screener reveals cognitive impairment, defined by a score of \>3 (possible range: 0-6) on MMSE cognitive screen (obtained from phone screener), or
* if the eligibility screener reveals active suicidal ideation, or
* severe hearing/speech impairment.

Where this trial is running

Indianapolis, Indiana

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions PainChronic PainSelf managementPain management
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.