Exploring neuroinflammation and oxidative stress after heart surgery
Assessing Neuroinflammation and Oxidative Stress After Cardiac Surgery: Unveiling Molecular Dynamics and Clinical Outcomes
This study looks at how inflammation and stress in the brain after heart surgery affect thinking and recovery in patients.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 60 Years |
| Sex | All |
| Sponsor | Europainclinics z.ú. Academic / other |
| Locations | 1 site (Košice) |
| Trial ID | NCT06391866 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the relationship between neuroinflammation and oxidative stress in patients who have undergone cardiac surgery, with a specific focus on postoperative cognitive dysfunction. It aims to assess how these factors influence cognitive function and overall well-being in the period following surgery. By examining the molecular mechanisms involved, the study seeks to understand the long-term effects of these processes on patients' recovery and cognitive health.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals undergoing cardiac surgery who do not have a history of neurological disease.
Not a fit: Patients with existing neurological diseases or those who refuse to participate may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved strategies for managing cognitive dysfunction in patients after cardiac surgery.
How similar studies have performed: While the interplay of neuroinflammation and oxidative stress has been explored in other contexts, this specific focus on postoperative cognitive dysfunction in cardiac surgery is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Undergoing cardiosurgical operation * Absence of previous neurological disease * Signed informed consent document Exclusion Criteria: * Presence of neoplasms * Neurological Disease * Refusal to participate in the clinical trial
Where this trial is running
Košice
- Europainclinics — Košice, Slovakia (Recruiting)
Study contacts
- Study coordinator: Ladislav Kočan, MD, PhD, FIPP
- Email: europainclinicsstudy@gmail.com
- Phone: +421557891110
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.