Exploring loneliness and mental health in post-COVID rehabilitation patients

Coping With Covid-19: Loneliness, Self-Efficacy, Social Support and Depression and Anxiety in Patients in Medical Rehabilitation. A Field Study in Geriatrics and Physical Medicine

Not applicable Interventional Helios Research Center · NCT05000255

This study is trying to see how loneliness and social support affect mental health in people recovering from COVID-19 and if certain activities can help improve their mood.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment300 (estimated)
Ages18 Years and up
SexAll
SponsorHelios Research Center Academic / other
Locations2 sites (Berlin and 1 other locations)
Trial IDNCT05000255 on ClinicalTrials.gov

What this trial studies

This study investigates the predictors and factors associated with mental health issues such as depression and anxiety in hospitalized patients recovering from COVID-19, as well as non-COVID patients in Germany. It aims to understand the relationships between loneliness, self-efficacy, and social support, and to evaluate the effectiveness of psychological interventions on these mental health outcomes. The research will utilize both correlational methods and experimental group comparisons to assess the impact of physical and social activities on mental health. The study is grounded in established psychological theories related to loneliness and self-efficacy.

Who should consider this trial

Good fit: Ideal candidates include adults aged 18 and older who have been diagnosed with COVID-19 or non-COVID patients in need of early rehabilitation.

Not a fit: Patients with significant cognitive impairments or language barriers may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved mental health interventions for patients recovering from COVID-19 and enhance overall rehabilitation outcomes.

How similar studies have performed: Other studies have shown promising results in addressing mental health issues in post-COVID patients, suggesting that this approach may be effective.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* patients aged 18 years to no upper limit
* patients were diagnosed with COVID-19
* Non-COVID patients with the need to participate in early rehab

Exclusion Criteria:

* a too high language barrier or dyslexia
* patients with intellectual and cognitive impairment (like primary psychiatric illness, e.g., schizophrenia or dementia, if admitted by means of medical history by a physician or if the score achieved in the cognitive screening by means of the mini-mental-state-examination (MMSE) is 23 or below 23 and no improvement of the cognitive performance is to be expected, e.g. because of an incipient dementia)

Where this trial is running

Berlin and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions LonelinessDepression, AnxietySelf EfficacySocial SupportCovid19PsychologyLoneliness, Depression, Anxiety, Post-COVID, COVID-19, Psych
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.