Exploring how psychological stress affects breast cancer treatment outcomes

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the relationship between psychological stress and the effectiveness of neoadjuvant chemotherapy in breast cancer patients. It focuses on treatment-naive individuals who have a confirmed diagnosis of breast cancer and are set to receive standard neoadjuvant therapy. The study aims to assess how factors such as anxiety and depression may influence the therapeutic response, given that emotional distress is prevalent among cancer patients. By understanding these dynamics, the research seeks to shed light on the potential impact of psychological factors on cancer treatment outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 1.Age ≥ 18 years; 2.Histological and/or cytological diagnosis of breast cancer; 3.Treatment niave patients; 4.To receive standard neoadjuvant therapy; 5.Eastern Cooperative Oncology Group (ECOG) performance status of 0-1; 6.Presence of at least one measurable lesion according to the Response Evaluation Criteria in Advanced Solid Tumors version 1.1 (RECIST v1.1) ; 7.Informed and agreed to participate in the study;

Exclusion Criteria:

* 1\. Breast cancer has not been confirmed through histological or cytological examinations.

  2.Other breast cancer conditions that do not receive neoadjuvant therapy. 3.Combined with other malignant tumors. 4.Concurrent acute or chronic psychiatric disorders, along with having received antidepressant or anti-anxiety therapy within the past month.

  5.Participants must not have engaged in any other clinical trials in the past month, unless those trials are observational or non-interventional in nature.

Where it's running

• Shengjing Hospital of China Medical University
  Shenyang, Liaoning, China Recruiting

Study contacts

• Study coordinator: Liu Hua, Ph. D
• Email: 20242027@cmu.edu.cn
• Phone: 15140067366

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.