Exploring how musical training affects brain plasticity in dyslexic adolescents
Neuroplasticity of Multisensory Cortical Areas Induced by Computerized Musical Training, Across the Life Span: a Translational Approach
This study is testing if musical training can help improve brain function and perception in teenagers with dyslexia.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 75 (estimated) |
| Ages | 12 Years to 100 Years |
| Sex | All |
| Sponsor | Aristotle University Of Thessaloniki Academic / other |
| Locations | 1 site (Thessaloníki) |
| Trial ID | NCT03786185 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of musical training on neuroplasticity in adolescents with dyslexia. Utilizing a computer-based multisensory training protocol, the research aims to enhance audiovisual perception and understand the underlying cortical networks involved. High-density EEG measurements will be employed to assess changes in brain activity and connectivity before and after the training. The study also compares the developmental trajectories of multisensory integration in both dyslexic adolescents and healthy controls.
Who should consider this trial
Good fit: Ideal candidates for this study are adolescents aged 13 to 18 who have been diagnosed with dyslexia.
Not a fit: Patients with other neurological, mental, or developmental disorders, or those with severe physical conditions, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve educational and therapeutic strategies for adolescents with dyslexia by leveraging musical training to enhance cognitive functions.
How similar studies have performed: While there is emerging evidence supporting the benefits of musical training on cognitive functions, this specific approach focusing on dyslexia and neuroplasticity is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Group of Adolescent dyslectics Inclusion Criteria: * 13 - 18 years of age * normal or corrected-to-normal hearing and vision * Diagnosed dyslexia Exclusion Criteria: * any other than dyslexia, diagnosed neurological, mental, developmental or psychiatric disorder * (ii) unrecovered neurological disorders (i.e., stroke, traumatic brain injury), * (iii) unstable medication within the last 3 months, * (iv) severe physical disorder, and * (v) concurrent participation in another relevant study. Group of Adolescent controls Inclusion Criteria: * 13 - 18 years of age * normal or corrected-to-normal hearing and vision Exclusion Criteria: * (I) any diagnosed neurological, mental, developmental or psychiatric disorder * (ii) unrecovered neurological disorders (i.e., stroke, traumatic brain injury), * (iii) unstable medication within the last 3 months, * (iv) severe physical disorder, and * (v) concurrent participation in another relevant study. Group of Young Adults Inclusion Criteria: * 18 - 35 years of age * normal or corrected-to-normal hearing and vision Exclusion Criteria: * (I) any diagnosed neurological, mental, developmental or psychiatric disorder * (ii) unrecovered neurological disorders (i.e., stroke, traumatic brain injury), * (iii) unstable medication within the last 3 months, * (iv) severe physical disorder, and * (v) concurrent participation in another relevant study. Group of Seniors Inclusion Criteria: * 65 - 100 years of age * normal or corrected-to-normal hearing and vision * normal score in a neuropsychological screening procedure which regards cognitive functionality Exclusion Criteria: * (i) unrecovered neurological disorders (i.e., stroke, traumatic brain injury), * (ii) severe depression or psychological disorder, * (iii) unstable medication within the last 3 months, * (iv) severe physical disorder, and * (v) concurrent participation in another relevant study.
Where this trial is running
Thessaloníki
- Laboratory of Medical Physics — Thessaloníki, Greece (Recruiting)
Study contacts
- Principal investigator: Evangelos Paraskevopoulos, PhD — Research Associate
- Study coordinator: Evangelos Paraskevopoulos, PhD
- Email: parasvag@auth.gr
- Phone: +306944141615
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.