Exploring how knee pain affects walking
Undersøgelse af sammenhængen Mellem Biomekanik og Smerter Ved Gang
This study tests how knee pain affects walking in healthy people by giving them two types of knee injections and looking at changes in their walking patterns.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 34 (estimated) |
| Ages | 18 Years to 45 Years |
| Sex | All |
| Sponsor | Aalborg University Academic / other |
| Locations | 1 site (Aalborg, Nordjylland) |
| Trial ID | NCT06330402 on ClinicalTrials.gov |
What this trial studies
This interventional study investigates the biomechanics of gait in healthy individuals experiencing experimental knee pain. Participants will receive two types of knee injections: hypertonic saline to induce pain and isotonic saline as a control. Using a randomized, crossover design, the study will analyze changes in walking patterns and pain sensitivity through motion capture and cuff-pressure testing. The goal is to understand how pain influences gait and whether these changes can predict pain intensity.
Who should consider this trial
Good fit: Ideal candidates are healthy men and women aged 18-45 years.
Not a fit: Patients with current pain, neurological or musculoskeletal illnesses, or those who are pregnant will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of pain mechanisms and improve treatment strategies for knee pain.
How similar studies have performed: While studies on gait biomechanics exist, this specific approach using hypertonic saline for pain induction is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Healthy men and women aged 18-45 years Exclusion Criteria: * Pregnancy * Drug addiction, defined as the use of cannabis, opioids, or other drugs * Previous or current neurologic or musculoskeletal illnesses * Current pain * Lack of ability to cooperate
Where this trial is running
Aalborg, Nordjylland
- Aalborg University — Aalborg, Nordjylland, Denmark (Recruiting)
Study contacts
- Study coordinator: Kristian K Petersen, Dr. Med
- Email: kkp@hst.aau.dk
- Phone: (+45) 31697510
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.