Exploring how gender affects liver aging
Exploration of Gender Differences in Liver Aging
This study looks at how aging affects liver health differently in men and women to see if these differences might lead to more liver problems as people get older.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 18 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | Second Affiliated Hospital, School of Medicine, Zhejiang University Academic / other |
| Locations | 1 site (Hangzhou, Zhejiang) |
| Trial ID | NCT06591897 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the differences in liver aging between genders in a healthy population. It aims to understand how metabolic and immune functions in the liver change with age and how these changes may lead to increased susceptibility to liver-related diseases in older adults. By examining liver function indicators and imaging results, the study seeks to provide insights into the regulatory mechanisms of liver aging. The findings could help clarify the role of gender in liver health and aging.
Who should consider this trial
Good fit: Ideal candidates for this study are healthy individuals with normal liver function indicators and imaging results.
Not a fit: Patients with previous liver-related diseases or significant organ dysfunction will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance our understanding of liver aging and lead to better prevention strategies for liver-related diseases in the elderly.
How similar studies have performed: While there is ongoing research into liver aging, this specific focus on gender differences is relatively novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Liver function indicators are in the normal reference range. * Liver imaging examination showed normal. Exclusion Criteria: * Patients with previous liver-related diseases. * Subjects with important organ dysfunction / failure or other serious diseases ( myocardial infarction, malignant tumor, severe neurological or psychiatric history, severe infection, coagulation dysfunction, etc. ) * Moderate malnutrition ( BMI \< 17kg / m2 ) and severe anemia ( Hb \< 60g / L ). * Subjects and their families who disagreed with the study protocol.
Where this trial is running
Hangzhou, Zhejiang
- 2nd Affiliated Hospital, School of Medicine, Zhejiang University, China — Hangzhou, Zhejiang, China (Recruiting)
Study contacts
- Study coordinator: daren Liu, MD, PhD
- Email: darenliu@zju.edu.cn
- Phone: 15968179036
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.