Exploring how dissection depth affects scar formation in early gastric cancer treatment

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the relationship between the depth of endoscopic submucosal dissection (ESD) and the resulting scar formation in patients with early gastric cancer. It is a single-center, prospective, group-controlled study that aims to compare scar sizes resulting from different dissection depths and assess their impact on gastric function and patient prognosis. The findings are intended to provide evidence-based guidelines for ESD treatment in early gastric cancer, ultimately leading to improved clinical techniques and patient outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients older than 18 years old and younger than 75 years old.
* Early gastric cancer (T1a stage) diagnosed by gastroscopy or ultrasonography, differentiated and no ulcer; or early gastric cancer (T1a stage), differentiated with ulcer, lesion diameter \<3cm; or early gastric cancer (T1a stage), undifferentiated and No ulcer, lesion diameter \<2cm.
* Pathological diagnosis of gastric cancer.
* No further treatment is required.
* Patients diagnosed for the first time without other serious gastrointestinal diseases.

Exclusion Criteria:

* Those who did not comply with the test requirements, obviously violated this protocol, or switched to other protocols in the middle of treatment.
* Advanced gastric cancer; or undifferentiated gastric cancer lesions \> 2 cm in diameter; or differentiated gastric cancer with ulcer lesions \> 3 cm in diameter.
* Coagulation disorders.
* Serious heart, liver, kidney and other diseases, can not tolerate ESD treatment.
* Patients with gastric cancer complications such as gastrointestinal bleeding and perforation that need emergency treatment.
* Patients with distant metastasis.
* Patients with other tumors, patients with a history of malignant tumors (except early carcinoma in situ.
* The patient himself requests to withdraw from the trial.
* The researcher believes that the patient is not suitable to participate in this study.

Where it's running

• Second affiliated hospital, school of medicine, Zhejiang University
  Hangzhou, Zhejiang, China Recruiting

Study contacts

• Study coordinator: Yuqi Wang, Doctor
• Email: wyq@zju.edu.cn
• Phone: +86-15267019821

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Using a robotic system to improve safety and efficiency in treating early gastric cancer

  This study is testing if a new robotic system can make the treatment for early gastric cancer safer and quicker compared to the usual method.

  Recruiting Shandong University · Jinan, Shandong · NCT06748352

• SPADE procedure for upper stomach cancer

  A multicenter study will test the SPADE operation, a special stomach reconnection technique, in patients with early upper-stomach cancer undergoing proximal gastrectomy to see if it is safe and feasible.

  Recruiting National Cancer Center, Korea · Goyang, Gyeonggido · NCT07892183

• LECS with sentinel node navigation for early gastric cancer

  This study tests whether combining LECS with sentinel node navigation can treat early gastric cancer while preserving stomach function in eligible patients.

  Recruiting Peking University People's Hospital · Beijing, Beijing Municipality · NCT07857668

• Image-guided platform helps find sentinel lymph nodes in early gastric cancer

  This study tests whether an image-guided platform with a deep learning model can find and retrieve sentinel lymph nodes better than standard palpation in people with early gastric cancer undergoing LECS-SNNS.

  Recruiting Beijing Friendship Hospital · Beijing · NCT07835087

• Early Gastric Cancer in China: Real-World Outcomes by Treatment Type

  This project will look at real-world outcomes for about 5,000 Chinese patients with early gastric cancer treated with endoscopic resection, laparoscopic surgery, open surgery, or a combined approach to see how treatments relate to survival and recurrence.

  Recruiting Beijing Friendship Hospital · Beijing · NCT07747688

• H. pylori status and tissue features to predict gastric cancer behavior after endoscopic treatment

  This study tests whether current H. pylori infection status and tissue features can help predict how early gastric cancer will behave after endoscopic treatment.

  Recruiting at 3 sites Chinese PLA General Hospital · Beijing, Beijing Municipality and 2 other locations · NCT07724496

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.