Exploring how cognitive reappraisal can enhance positive emotions

Investigating the Neural Systems That Support the Reappraisal Tactics Leading to Positive Emotion

NA · University of Denver · NCT04532242

This study is testing if teaching people how to change their thoughts can help them feel more positive emotions while their brain activity is being monitored.

Quick facts

PhaseNA
Study typeInterventional
Enrollment40 (estimated)
Ages18 Years to 55 Years
SexAll
SponsorUniversity of Denver (other)
Locations1 site (Denver, Colorado)
Trial IDNCT04532242 on ClinicalTrials.gov

What this trial studies

This study investigates the neural mechanisms involved in cognitive reappraisal, a technique used to manage negative emotions by changing one's perspective on a situation. Participants aged 18-55 will undergo a single session at the neuroimaging facility at CU Boulder, where they will be trained in cognitive reappraisal techniques and then engage in a picture-based task while their brain activity is monitored using fMRI. The study aims to assess the impact of this training on self-reported emotions before and after the task. Data collected will help understand how cognitive strategies can influence emotional responses.

Who should consider this trial

Good fit: Ideal candidates for this study are community members aged 18-55 who are fluent in English and do not exhibit psychotic symptoms.

Not a fit: Patients with current psychotic symptoms may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide insights into effective strategies for enhancing emotional well-being and managing negative emotions.

How similar studies have performed: Previous studies have shown promising results in using cognitive reappraisal techniques to improve emotional regulation, indicating potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Community members ages 18-55
* Fluent in English
* Without present psychotic symptoms

Exclusion Criteria:

* None

Where this trial is running

Denver, Colorado

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Behavior, cognitive reappraisal, cognition

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.