Exploring how autonomy affects motor learning in Parkinson's disease
Influence of Autonomy on Motor Learning in People With Parkinson's Disease
This study is testing if allowing people with Parkinson's disease to choose how they receive feedback during practice can help them learn better and feel more motivated.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 72 (estimated) |
| Ages | 20 Years and up |
| Sex | All |
| Sponsor | National Taiwan University Hospital Academic / other |
| Locations | 1 site (Taipei) |
| Trial ID | NCT05960331 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the impact of autonomy-supported learning on motor learning in individuals with Parkinson's disease. Participants will be divided into two groups: one with the ability to choose their feedback schedule during practice and another that receives predetermined feedback. The study aims to assess whether this autonomy can enhance intrinsic motivation, improve information processing, and facilitate changes in cortical excitability. Learning outcomes will be evaluated through performance tests conducted on the second day and one week later, alongside assessments of motivation and cortical plasticity using transcranial magnetic stimulation.
Who should consider this trial
Good fit: Ideal candidates are adults over 20 years old with Parkinson's disease who can follow instructions and have no recent upper extremity injuries.
Not a fit: Patients with other neurological disorders, severe tremors, or those who have undergone deep brain stimulation may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to improved motor learning and motivation in patients with Parkinson's disease.
How similar studies have performed: While the concept of autonomy-supported learning is gaining interest, this specific approach in Parkinson's disease is relatively novel and has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * age above 20-years-old * able to follow instructions to perform the tasks (Montreal Cognitive Assessment ≥ 24) * no surgery and injury in upper extremities in recent 6 months Exclusion Criteria: * other neurological disorders in addition to Parkinson's disease * Parkinson's disease dementia * symptom of severe tremor in upper extremities (score ≥ 3 in Question 15 to 18 of UPDRS-III) * deep brain stimulation or pacemaker implanted * medical history of seizure * a blood-relative with history of epilepsy * unstable medical conditions * pregnancy
Where this trial is running
Taipei
- National Taiwan University Hospital — Taipei, Taiwan (Recruiting)
Study contacts
- Study coordinator: YA-YUN LEE, PhD
- Email: yayunlee@ntu.edu.tw
- Phone: +886-2-33668155
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.