Exploring how 3D printed prostheses affect brain activity in children

The Influence of 3D Printed Prostheses on Neural Activation Patterns of the Primary Motor Cortex in Children With Unilateral Congenital Upper-limb Reductions

NA · University of Nebraska · NCT04110730

This study is testing how using 3D printed prosthetic arms affects brain activity in children with upper-limb differences compared to typically developing kids.

Quick facts

PhaseNA
Study typeInterventional
Enrollment40 (estimated)
Ages3 Years to 18 Years
SexAll
SponsorUniversity of Nebraska (other)
Locations1 site (Omaha, Nebraska)
Trial IDNCT04110730 on ClinicalTrials.gov

What this trial studies

This study investigates the neural activation patterns in children using 3D printed prostheses for upper-limb deformities. It aims to enroll 40 children aged 3 to 18, including those with congenital upper-limb reductions and a control group of typically developing children. Participants will undergo 3D scanning and fitting of the prosthesis, followed by assessments of motor performance and brain activity using functional near-infrared spectroscopy (fNIRS). The goal is to enhance understanding of how prosthesis use influences motor cortex activity and to inform rehabilitation strategies.

Who should consider this trial

Good fit: Ideal candidates are children aged 3 to 18 with upper limb deformities or missing digits.

Not a fit: Patients with recent upper extremity injuries or medical conditions that contraindicate prosthetic use may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved rehabilitation programs that reduce prosthesis rejection and enhance motor performance in children.

How similar studies have performed: While the specific use of 3D printed prostheses in this context is novel, related studies have shown promise in understanding neural activation patterns in prosthesis users.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 3-18 years.
* Individuals missing any digits, hand, arm, shoulder.
* Any dysfunction of the upper limbs.

Exclusion Criteria:

* Participants who are outside of age range.
* Participants with upper extremity injury within the past month.
* Medical conditions which would be contraindications to wear a prosthetic or assistive device, Such as skin abrasions and musculoskeletal injuries in the upper limbs.

Where this trial is running

Omaha, Nebraska

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Amniotic Band Syndrome, Upper Extremity Deformities, Congenital

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.