Clinical trial Recruiting at 1 site Observational Ages 18 and up

Exploring genetic factors in pulmonary fibrosis

Official title: Idiopathic Pulmonary Fibrosis, a Disease Initiated by Mucociliary Dysfunction

Run by University of Colorado, Denver · NCT03478553 · Data updated 2026-11-12

This study is trying to see if there are genetic links to pulmonary fibrosis by testing family members of patients with the condition for early signs of lung issues.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment1000 (estimated)
SponsorUniversity of Colorado, Denver
Academic / other
Locations1 site (Aurora, Colorado)
StatusRecruiting
StartedJanuary 18, 2018
Main results expectedDecember 31, 2026
Study endsDecember 31, 2026
Registry record updatedMarch 25, 2025
Trial IDNCT03478553 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults aged 18 and older who have a family member diagnosed with Idiopathic Pulmonary Fibrosis.

Probably not a fit

Patients without a family member diagnosed with IPF will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to screen first-degree family members of individuals diagnosed with Idiopathic Pulmonary Fibrosis (IPF) for early signs of lung fibrosis. The researchers will investigate genetic factors and environmental exposures that may contribute to the development of pulmonary fibrosis. By enrolling both patients with pulmonary fibrosis and their family members, the study seeks to identify genetic loci associated with this condition. Blood samples and questionnaires will be utilized to gather necessary data.

Why it matters

Potential benefit: If successful, this study could lead to early detection and better understanding of genetic risks for pulmonary fibrosis in at-risk individuals.

How similar studies have gone: While genetic studies in pulmonary fibrosis are ongoing, this specific approach focusing on first-degree relatives is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age at least 18 years old
* Family member diagnosed with IPF

Exclusion Criteria:

\- No family member with IPF

Where it's running

  • University of Colorado Anschutz Medical Campus
    Aurora, Colorado, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.