Exploring genetic factors in pulmonary fibrosis
Idiopathic Pulmonary Fibrosis, a Disease Initiated by Mucociliary Dysfunction
University of Colorado, Denver · NCT03478553
This study is trying to see if there are genetic links to pulmonary fibrosis by testing family members of patients with the condition for early signs of lung issues.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Colorado, Denver (other) |
| Locations | 1 site (Aurora, Colorado) |
| Trial ID | NCT03478553 on ClinicalTrials.gov |
What this trial studies
This observational study aims to screen first-degree family members of individuals diagnosed with Idiopathic Pulmonary Fibrosis (IPF) for early signs of lung fibrosis. The researchers will investigate genetic factors and environmental exposures that may contribute to the development of pulmonary fibrosis. By enrolling both patients with pulmonary fibrosis and their family members, the study seeks to identify genetic loci associated with this condition. Blood samples and questionnaires will be utilized to gather necessary data.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older who have a family member diagnosed with Idiopathic Pulmonary Fibrosis.
Not a fit: Patients without a family member diagnosed with IPF will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to early detection and better understanding of genetic risks for pulmonary fibrosis in at-risk individuals.
How similar studies have performed: While genetic studies in pulmonary fibrosis are ongoing, this specific approach focusing on first-degree relatives is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age at least 18 years old * Family member diagnosed with IPF Exclusion Criteria: \- No family member with IPF
Where this trial is running
Aurora, Colorado
- University of Colorado Anschutz Medical Campus — Aurora, Colorado, United States (RECRUITING)
Study contacts
- Principal investigator: David A Schwartz, MD — University of Colorado, Denver
- Study coordinator: Rachel Warren
- Email: rachel.warren@cuanschutz.edu
- Phone: 303-724-8569
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Idiopathic Pulmonary Fibrosis