Exploring genetic factors in chronic sinusitis
Genetic Factors in Chronic Sinusitis
University of Chicago · NCT00880516
This study is looking to see if certain genes are linked to chronic sinusitis by comparing people with the condition to those without it.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1200 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Chicago (other) |
| Locations | 1 site (Chicago, Illinois) |
| Trial ID | NCT00880516 on ClinicalTrials.gov |
What this trial studies
This observational study aims to investigate the genetic components associated with chronic sinusitis. By analyzing participants with either chronic sinusitis or normal sinuses, the researchers will identify specific genes that may play a role in this condition. Participants will undergo imaging verification through recent CT scans to confirm their diagnosis. The study seeks to enhance understanding of the genetic underpinnings of chronic sinusitis, potentially leading to improved treatment strategies.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 years old with a diagnosis of chronic sinusitis or normal sinuses confirmed by imaging.
Not a fit: Patients with genetic or acquired immunodeficiencies, ciliary dyskinesia, cystic fibrosis, autoimmune diseases, or sinus cancer may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to targeted therapies and personalized treatment options for patients suffering from chronic sinusitis.
How similar studies have performed: While genetic studies in chronic sinusitis are not extensively documented, similar approaches in other conditions have shown promise in identifying genetic factors and improving treatment outcomes.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age\> 18 years * Diagnosis of chronic sinusitis or normal sinuses (with verification by imaging.) You must have a recent CT scan showing either normal sinuses or the presence of sinus disease. Exclusion Criteria: * Genetic or acquired immunodeficiency * Ciliary dyskinesia * Cystic fibrosis * Autoimmune disease * Cancer of the sinuses
Where this trial is running
Chicago, Illinois
- University of Chicago — Chicago, Illinois, United States (RECRUITING)
Study contacts
- Principal investigator: Jayant Pinto, MD — University of Chicago
- Study coordinator: Marcy deTineo, BSN
- Email: mdetineo@surgery.bsd.uchicago.edu
- Phone: 773-702-5889
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Chronic Sinusitis