Exploring genetic factors in childhood asthma

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the association between genetic single nucleotide polymorphisms (SNPs) and type 2 inflammation-related asthma in children. It involves analyzing SNPs, lung function, and type 2 inflammation indicators in children diagnosed with asthma, comparing them to healthy controls. The goal is to identify genetic risk factors that may contribute to asthma and to provide insights for personalized treatment and prevention strategies.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. All children with asthma diagnosis accord with the GINA in 2023 edition;
2. Other diseases that could cause wheezing and cough were excluded, such as acute laryngitis, diphtheria, congenital airway abnormalities, and tracheal foreign bodies;
3. In front of the hospital 2 weeks without antibiotics, systemic hormone medication history;
4. There were no other complications, such as congenital heart disease, pneumonia, gastroesophageal reflux disease, muscle dysplasia, etc.

Exclusion Criteria:

1. Children who had taken immunosuppressants, antibiotics and other drugs for a long time before admission;
2. Children with primary immunodeficiency disease;
3. The children and their families failed to cooperate or refused the experimental observation.

Where it's running

• Guangzhou institute of respiratory disease
  Guangzhou, Guangdong, China Recruiting

Study contacts

• Study coordinator: Lihong Sun, M.D.
• Email: sunlihong9797@126.com
• Phone: 13719240285

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.