Exploring factors affecting the effectiveness of levamlodipine besylate in treating hypertension
Analysis of Factors Influencing the Efficacy of Levamlodipine Benzoate and Its Population Pharmacodynamic Modeling
The Second Affiliated Hospital of Chongqing Medical University · NCT05958524
This study looks at how different factors like age, medical history, and other medications affect how well levamlodipine besylate works for people who have just been diagnosed with high blood pressure.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 150 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | The Second Affiliated Hospital of Chongqing Medical University (other) |
| Locations | 1 site (Chongqing) |
| Trial ID | NCT05958524 on ClinicalTrials.gov |
What this trial studies
This observational study aims to analyze the factors influencing the efficacy of levamlodipine besylate in newly diagnosed hypertensive patients. It will collect and evaluate outpatient medical records to assess how demographic factors, personal history, combined medications, and biochemical indicators affect blood pressure control. By establishing a population pharmacokinetic model, the study seeks to provide insights for individualized treatment and rational drug use in hypertension management.
Who should consider this trial
Good fit: Ideal candidates are newly diagnosed hypertensive patients who are starting treatment with levamlodipine besylate.
Not a fit: Patients who are not newly diagnosed or those who have been treated with other antihypertensive medications will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more personalized and effective treatment strategies for patients with hypertension.
How similar studies have performed: While similar pharmacodynamic modeling approaches have been explored, this specific analysis of levamlodipine besylate's efficacy in hypertension is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Newly diagnosed patients with hypertension in our hospital (sex, age is not limited). 2. Patients whose initial treatment is levamlodipine besylate. Exclusion Criteria: 1. Patients who cannot be followed up regularly or are lost to follow-up after initial diagnosis and treatment. 2. Patients who were initially treated with other antihypertensive drugs. 3. Blood pressure was not measured when the patient came to the hospital for follow-up.
Where this trial is running
Chongqing
- Yu Xian — Chongqing, China (RECRUITING)
Study contacts
- Principal investigator: Xian Yu — The Second Affiliated Hospital of Chongqing Medical University
- Study coordinator: Xian Yu, professor
- Email: 1clinicaltrial@hospital.cqmu.edu.cn
- Phone: 18512356862
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Hypertensive Patients, Monotherapy, levamlodipine besylate；monotherapy；, Population pharmacodynamics