Exploring factors affecting symptoms in women with multiple sclerosis

Exploratory Study on the Timing of MS Symptoms

University of Louisville · NCT00919217

This study is trying to see how things like stress, hormones, and missed medications affect the symptoms of relapsing-remitting multiple sclerosis in women.

Quick facts

Study typeObservational
Enrollment80 (estimated)
Ages18 Years to 50 Years
SexFemale
SponsorUniversity of Louisville (other)
Drugs / interventionschemotherapy
Locations1 site (Louisville, Kentucky)
Trial IDNCT00919217 on ClinicalTrials.gov

What this trial studies

This observational study investigates how various factors such as stress, hormonal cycles, illnesses, and missed medications influence the symptoms of relapsing-remitting multiple sclerosis (RR-MS) in women. Participants will maintain a daily diary and calendar for 90 days to document their symptoms and any relevant factors. The data collected will be analyzed statistically to identify which factors significantly impact symptom fluctuations. Participants will receive compensation for their time and effort in completing the diaries.

Who should consider this trial

Good fit: Ideal candidates for this study are females diagnosed with relapsing-remitting multiple sclerosis.

Not a fit: Patients who are male, have other autoimmune diseases, or are peri-, post-, or surgically menopausal may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could help identify triggers for MS symptoms, leading to better management strategies for patients.

How similar studies have performed: While this approach is exploratory, similar observational studies have provided valuable insights into symptom management in chronic conditions.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* females
* diagnosed with relapsing-remitting multiple sclerosis

Exclusion Criteria:

* male
* no diagnosis of relapsing-remitting MS
* diagnosis of any other autoimmune disease or fibromyalgia
* peri-, post-, or surgically menopausal
* pregnant within past year or nursing
* history of chemotherapy
* on experimental medications
* treatment with steroids in the last 30 days

Where this trial is running

Louisville, Kentucky

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Relapsing Remitting Multiple Sclerosis, Multiple Sclerosis, MS, Relapsing-remitting multiple sclerosis, RR-MS, Women

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.