Exploring body temperature targets in heat stroke patients

Early Body Temperature Targets and Relationship With Prognosis in Patients With Heat Stroke

Observational Second Affiliated Hospital, School of Medicine, Zhejiang University · NCT05921682

This study is trying to find the best body temperature targets and cooling methods for people with heat stroke to see if it helps them recover better.

Quick facts

Study typeObservational
Enrollment100 (estimated)
Ages18 Years and up
SexAll
SponsorSecond Affiliated Hospital, School of Medicine, Zhejiang University Academic / other
Locations6 sites (Yiwu, Zhejiang and 5 other locations)
Trial IDNCT05921682 on ClinicalTrials.gov

What this trial studies

This observational study aims to determine the optimal body temperature targets within the first 24 hours for patients diagnosed with heat stroke and to investigate the relationship between body temperature and adverse outcomes. It will assess key time points for body temperature measurements and evaluate the effectiveness of cooling interventions, including the volume and speed of ice saline infusion. By analyzing these factors, the study seeks to provide insights into improving patient outcomes in heat stroke cases.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 and older who have been diagnosed with heat stroke.

Not a fit: Patients requiring immediate cardiopulmonary resuscitation or those with severe underlying organ insufficiency may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved management strategies for heat stroke, potentially reducing adverse outcomes and enhancing recovery.

How similar studies have performed: While there have been studies on heat stroke management, this specific approach to optimizing body temperature targets is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* ≥ 18 years; ② diagnosed as heat stroke; ③ Informed consent from patients or family members.

Exclusion Criteria:

* need immediate cardiopulmonary resuscitation; ② transferred from another hospital; ③ with severe underlying organ insufficiency; ④ pregnant women.

Where this trial is running

Yiwu, Zhejiang and 5 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Heat Strokeheat stroke, body temperature, outcomes
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.