Exploring Apathy After Minor Stroke and Transient Ischemic Attack

Non-disabling Ischemic Cerebrovascular Event With Apathy: A Prospective Registry Trail

Observational Changhai Hospital · NCT04917237

This study looks at how feeling apathetic after a minor stroke or TIA affects recovery and the chances of having another stroke in adults during their first year after the event.

Quick facts

Study typeObservational
Enrollment200 (estimated)
Ages18 Years to 80 Years
SexAll
SponsorChanghai Hospital Academic / other
Locations1 site (Shanghai, Shanghai)
Trial IDNCT04917237 on ClinicalTrials.gov

What this trial studies

This observational study investigates the relationship between baseline apathy and the likelihood of subsequent strokes in adults who have experienced transient ischemic attacks (TIA) or minor strokes. It aims to establish the prevalence and predictors of post-stroke apathy (PSA) in these patients during the first year following their initial event. By focusing on this often-overlooked aspect of recovery, the study seeks to enhance understanding of how apathy affects functional recovery and quality of life in stroke survivors.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 and older who have recently experienced a minor stroke or transient ischemic attack.

Not a fit: Patients with severe comorbid conditions, such as malignant tumors or severe liver or kidney disease, may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved recognition and management of apathy in stroke patients, potentially enhancing their recovery and quality of life.

How similar studies have performed: Previous studies have indicated that post-stroke apathy is a significant issue affecting recovery, suggesting that this study's focus on TIA and minor stroke patients is both relevant and necessary.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

≥18 years old Onset of a minor stroke (National Institute of Health stroke scale, NIHSS≤3) and TIA elapsed time from last episode to registry \<1 month

Exclusion Criteria:

patients who refused to participate in the research, and patients who failed to complete the follow-up protocol.

patients with malignant tumors, or patients with severe liver or kidney disease, whose life expectancy is less than 1 year.

patients who received endovascular or thrombolytic therapy.

Where this trial is running

Shanghai, Shanghai

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions ApathyMinor StrokeTransient Ischemic AttackStrokeminor stroke
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.