Exploring anxiety and depression risk factors in herpes zoster neuralgia patients
Official title: Risk Factors Analysis of Anxiety and Depression in Patients With Herpes Zoster Neuralgia and Characteristics of Serum Biomarkers and Functional Brain Magnetic Resonance Changes
Run by Huazhong University of Science and Technology · NCT06449547 · Data updated 2026-11-12
This study is trying to find out what factors might lead to anxiety and depression in people who have pain from shingles.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 600 (estimated) |
| Sponsor | Huazhong University of Science and Technology Academic / other |
| Locations | 1 site (Wuhan, Hubei) |
| Status | Recruiting |
| Started | June 21, 2024 |
| Main results expected | May 2026 |
| Study ends | December 2026 |
| Registry record updated | August 26, 2024 |
| Trial ID | NCT06449547 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults over 18 years old diagnosed with herpes zoster neuralgia who can provide informed consent.
✕Probably not a fit
Patients with a history of mental illness or those unable to complete the scale assessment may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to identify risk factors for anxiety and depression in patients suffering from herpes zoster neuralgia. Participants will undergo evaluations using the Hospital Anxiety and Depression Scale (HADS) to categorize them into groups based on their anxiety and depression levels. The study will collect and analyze clinical data, serum biomarkers, and functional brain MRI results to understand the relationship between these factors and the psychological conditions in affected patients.
Why it matters
Potential benefit: If successful, this study could lead to better understanding and management of anxiety and depression in patients with herpes zoster neuralgia.
How similar studies have gone: While similar studies have explored psychological factors in chronic pain conditions, this specific focus on herpes zoster neuralgia is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age more than 18 years old 2. Diagnosed as herpes zoster neuralgia 3. Signing informed consent Exclusion Criteria: 1. Unable to complete the scale assessment 2. History of mental illness
Where it's running
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Tongji hospital
Wuhan, Hubei, China Recruiting
Study contacts
- Principal investigator: Yang Shuguang, M.D — Tongji medical college of Huazhong University of Science and technology
- Study coordinator: Yang Shuguang, M.D
- Email: yangsuperpro@163.com
- Phone: (+86)15071078161
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Recombinant Zoster Vaccine with ZFA01 Adjuvant in Adults 40+
A two-part study tests a recombinant herpes zoster vaccine in healthy adults aged 40 and older to see if it boosts immune responses and is safe.
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How long the live shingles vaccine protects you
This will see if the live attenuated shingles vaccine keeps adults from the original Phase III trial protected against herpes zoster for up to six years after vaccination.
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Recombinant zoster (Shingrix) to see if it lowers new dementia diagnoses in people 76 and older in Finland.
This trial will test whether the Shingrix shingles vaccine lowers the chance of a new dementia diagnosis in people aged 76 or older who live in Finland.
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Erector spinae plane block versus transcutaneous radiofrequency for postherpetic neuralgia
This project will see if erector spinae plane block or transcutaneous radiofrequency works better to reduce pain in adults with postherpetic neuralgia.
-
Lyophilized shingles mRNA vaccine safety and immune response
This trial will test a lyophilized mRNA vaccine to see if it is safe and produces immune responses in adults aged 40 years and older.
-
Loxoprofen patch for relieving shingles pain
This will test if adding a loxoprofen sodium patch to standard care reduces pain in adults with shingles.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.