Exploring antibiotic resistance in patients with acute cholangitis
Exploring Antimicrobial Resistance in Patients With Acute Cholangitis Undergoing ERCP: A Prospective Multicentre Study
This study looks at how well current antibiotics work for patients with acute cholangitis by testing samples from their bile and blood to see if bacteria are resistant to treatment.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1700 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Emergency County Hospital Pius Brinzeu; Timisoara, Romania Research network |
| Locations | 1 site (Timisoara) |
| Trial ID | NCT06197984 on ClinicalTrials.gov |
What this trial studies
This observational study investigates antimicrobial resistance patterns in patients suffering from acute cholangitis who are undergoing endoscopic retrograde cholangiopancreatography (ERCP). It involves the collection and analysis of bile and blood samples to identify microbial cultures and assess the effectiveness of current antibiotic treatments. By adhering to established guidelines, the study aims to optimize treatment regimens based on the identified resistance patterns. The findings could provide valuable insights into managing infections associated with biliary tract diseases.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 years old diagnosed with acute cholangitis who can provide informed consent.
Not a fit: Patients under 18, pregnant individuals, or those unable to provide informed consent will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment strategies for patients with acute cholangitis, enhancing their recovery and outcomes.
How similar studies have performed: Other studies have shown success in identifying antimicrobial resistance patterns in similar conditions, indicating that this approach is both relevant and necessary.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with acute cholangitis * Ability to provide an informed consent * Age over 18 years * Any gender Exclusion Criteria: * Age under 18 * Pregnancy * Post-ERCP perforation * The patient's decision to abstain from study enrollment * Patients unable to express informed consent * Patients from whom a bile sample could not be collected.
Where this trial is running
Timisoara
- Bogdan Miutescu — Timisoara, Romania (Recruiting)
Study contacts
- Principal investigator: Bogdan Miutescu, MD,PhD — Emergency County Hospital Pius Brinzeu; Timisoara, Romania
- Study coordinator: Bogdan Miutescu, MD, PhD
- Email: bmiutescu@yahoo.com
- Phone: 0356433111
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.