Exploring a new treatment for high blood pressure using remote ischemic conditioning

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the safety and efficacy of remote ischemic conditioning as a treatment for essential hypertension in a community population. It aims to determine how this method can improve vascular function and regulate the body's response to hypertension. Participants will receive standard antihypertensive treatment alongside remote ischemic conditioning to assess its combined effects. The study is particularly relevant given the high prevalence of hypertension and its role as a leading risk factor for stroke.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age≥30 years, ≤ 75 years, regardless of sex;
2. Patients with a history of essential hypertension and systolic blood pressure (SBP) ≥140 mmHg in three blood pressure measurements performed on separate days within 3 days prior to enrollment.
3. Signed and dated informed consent is obtained.

Exclusion Criteria:

1. Blood pressure ≥ 180/110mmHg;
2. Planned adjustment of antihypertensive drugs within the next 3 weeks;
3. Severe hematologic disorders or significant coagulation abnormalities;
4. Individuals who had contraindication of remote ischemic conditioning, such as severe soft tissue injury, fracture or vascular injury in the upper limb, acute or subacute venous thrombosis, arterial occlusive disease, subclavian steal syndrome, etc;
5. Pregnant or lactating women;
6. Severe hepatic and renal dysfunction;
7. Patients being enrolled or having been enrolled in another clinical trial within the 3 months prior to this clinical trial;
8. Patients unsuitable for enrollment in the clinical trial according to the investigator's discretion.

Where it's running

• First Hospital of Jilin University
  Changchun, Jilin, China Recruiting

Study contacts

• Study coordinator: Yi Yang, MD,PhD
• Email: doctor_yangyi@163.com
• Phone: 0086-13756661217

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.