Clinical trial Recruiting at 1 site Interventional Ages 11 to 15

Exploring a new therapy for adolescents with PTSD

Official title: Clinical and Biomolecular Characteristics of Reminder-Focused Positive-Psychiatry in Adolescent With Posttraumatic Stress Disorder

Run by University of California, Los Angeles · NCT04529031 · Data updated 2026-11-12

This study is testing a new therapy called Reminder Focused Positive Psychiatry to see if it can help teenagers aged 11-15 with PTSD feel better.

Quick facts

Study typeInterventional
Ages11 Years to 15 Years
SexAll
Enrollment60 (estimated)
SponsorUniversity of California, Los Angeles
Academic / other
Locations1 site (Los Angeles, California)
StatusRecruiting
StartedApril 1, 2026
Main results expectedDecember 28, 2027
Study endsDecember 28, 2028
Registry record updatedMarch 27, 2026
Trial IDNCT04529031 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adolescents aged 11-15 years with a documented diagnosis of PTSD who can read and write in English.

Probably not a fit

Patients with intellectual disabilities, psychotic behaviors, or other specified neurodevelopmental disorders may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the clinical and biomolecular characteristics of Reminder Focused Positive Psychiatry (RFPP) in adolescents aged 11-15 years who have been diagnosed with posttraumatic stress disorder (PTSD). The research will involve recruiting 60 eligible adolescents from the Olive View UCLA Pediatrics Clinics, where they will be randomized into either the RFPP intervention group or an attentional control condition. The aim is to assess the feasibility and effectiveness of RFPP in improving PTSD symptoms and vascular function. Parental consent and adolescent assent will be obtained prior to participation.

Why it matters

Potential benefit: If successful, this intervention could significantly improve PTSD symptoms and overall mental health in adolescents.

How similar studies have gone: While RFPP is a novel approach, similar interventions have shown promise in improving PTSD symptoms in other populations.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Boy/Girl with documented PTSD,
* aged 11- 15 years old,
* able to read/write in English

Exclusion Criteria:

* presence of intellectual disabilities,
* presence of psychotic or self-injurious behavior,
* presence of seizure disorder,
* presence of language disorder,
* presence of eye disorders,
* presence of other neurodevelopmental disorders,
* presence of diagnosis of substance use disorder.

Where it's running

  • UCLA
    Los Angeles, California, United States
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.