Exploring a new programming method for Deep Brain Stimulation in Parkinson's Disease
Official title: Coordinated Reset Deep Brain Stimulation (RESET-DBS) and RESET-DBS - Extension (Sub-study)
Run by Boston Scientific Corporation · NCT03732898 · Data updated 2026-05-14
This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.
This study is testing a new way to program Deep Brain Stimulation for people with Parkinson's Disease to see if it works better than the usual methods.
Quick facts
| Study type | Interventional |
|---|---|
| Sex | All |
| Enrollment | 14 (estimated) |
| Sponsor | Boston Scientific Corporation Industry-sponsored |
| Locations | 2 sites (Berlin and 1 other locations) |
| Trial ID | NCT03732898 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals with Parkinson's Disease who have been implanted with DBS devices for at least three months and can tolerate extended periods without medication.
✕Probably not a fit
Patients with significant psychiatric issues or those who are pregnant or planning to become pregnant may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates a novel programming strategy for Deep Brain Stimulation (DBS) in patients with Parkinson's Disease (PD). It aims to assess the feasibility of this alternative approach compared to conventional programming techniques. Participants will have been receiving DBS therapy for at least three months and will undergo evaluations to determine the effectiveness of the new programming method. The study will involve a thorough assessment of patient responses and outcomes associated with the novel programming.
Why it matters
Potential benefit: If successful, this approach could enhance the effectiveness of DBS therapy for patients with Parkinson's Disease.
How similar studies have gone: While there have been various studies on DBS, this specific approach utilizing novel programming techniques is relatively novel and has not been extensively tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Key Inclusion Criteria: 1. Subject with PD implanted bilaterally in the STN and receiving DBS therapy for at least 3 months. 2. Tolerates \> 12 hours OFF medication and, per clinical judgment, be able to perform all study related procedures. 3. Able to understand the study requirements and the treatment procedures and must provide written informed consent before any study-specific tests or procedures are performed. Key Exclusion Criteria: 1. Exhibits significant psychiatric problems, including unrelated clinically significant depression as determined by the investigator. 2. A female who is pregnant, is breastfeeding, or is of childbearing potential and planning to get pregnant
Where it's running
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University Berlin, Charite Virchow
Berlin, Germany Recruiting -
Universitaetsklinikum Wuerzburg
Wuerzburg, Germany Recruiting
Study contacts
- Study coordinator: Cleo Mertz
- Email: BSNClinicalTrials@bsci.com
- Phone: 855-213-9890
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.