Exoskeleton-assisted gait training for stroke rehabilitation

Effects of Exoskeleton-Assisted Gait Training on Functional Rehabilitation Outcomes in Patients With Stroke

Not applicable Interventional University of Oklahoma · NCT03980457

This study is testing whether using a robotic exoskeleton during walking therapy can help stroke survivors recover better than regular walking exercises.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment50 (estimated)
Ages18 Years to 90 Years
SexAll
SponsorUniversity of Oklahoma Academic / other
Locations1 site (Oklahoma City, Oklahoma)
Trial IDNCT03980457 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the effectiveness of electromechanical exoskeleton-assisted gait training on rehabilitation outcomes for patients recovering from stroke. Conducted at the Oklahoma City VA Medical Center, it involves 50 patients who will receive standard therapy alongside either exoskeleton training or traditional over-ground gait training. The study will measure various functional outcomes, including independence and mobility, using established scales and assessments. Participants will be randomly assigned to either the experimental or control group, ensuring a robust comparison of the two approaches.

Who should consider this trial

Good fit: Ideal candidates are patients with acute ischemic or hemorrhagic stroke who are medically stable and able to stand independently.

Not a fit: Patients who are aphasic, confused, or medically unstable will not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly enhance rehabilitation outcomes and mobility for stroke patients.

How similar studies have performed: Previous studies have shown promise in using exoskeletons for rehabilitation, indicating potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. All patients with acute hemorrhagic or ischemic stroke documented clinically and by neuroimaging.
2. Medically stable from a cardio-respiratory stand point so that they can participate in daily therapies.
3. Depressed patients will be included in the study
4. Patients able to stand alone
5. Patients able to provide a written informed consent, from cognitively intact patients (admission Mini Mental Scale Examination \[MMSE\] greater than or equal to 21).

Exclusion Criteria:

1. Aphasic patients unable to communicate
2. Confused patients
3. Patients medically unstable
4. Patients unable to stand alone
5. Refusal to provide written informed consent

Where this trial is running

Oklahoma City, Oklahoma

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions StrokeWeakness of Extremities as Sequela of Strokeleg weaknessExoskeleton
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.