Exergaming versus neuromuscular exercise for older adults with Motoric Cognitive Risk
Official title: Effect of Exergaming Program Versus Neuromuscular Exercise on Locomotor and Cognitive Functions in Elderly People With Motor Cognitive Risk Syndrome
Run by Istanbul University - Cerrahpasa · NCT07045259 · Data updated 2026-11-12
This trial will test whether a video-game-based exercise program (exergaming) or a traditional neuromuscular exercise program better improves walking and thinking in people aged 65 and older with Motoric Cognitive Risk Syndrome.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 65 Years and up |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Istanbul University - Cerrahpasa Academic / other |
| Locations | 1 site (Balıkesir) |
| Status | Recruiting |
| Started | December 25, 2025 |
| Main results expected | November 30, 2026 |
| Study ends | December 30, 2026 |
| Registry record updated | October 8, 2026 |
| Trial ID | NCT07045259 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are ambulatory people aged 65 or older with subjective memory complaints, slow walking speed, preserved basic daily function (Barthel ≥90), and MMSE ≥24.
✕Probably not a fit
Patients with dementia, major depression, Parkinson's disease, significant sensory impairments, or medical conditions such as anemia, thyroid disease, vitamin B12 deficiency, malnutrition, or terminal illness are unlikely to qualify or benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Older adults meeting criteria for Motoric Cognitive Risk (slow gait plus subjective memory complaints, preserved basic function and MMSE ≥24) will be assigned to either a structured neuromuscular exercise program or a supervised exergaming exercise program delivered by trained staff. Both interventions involve regular, supervised training sessions over a defined intervention period, with baseline and post-intervention assessments. Primary outcomes include locomotor measures such as gait speed and mobility tests and cognitive measures such as global cognition and memory tests. The trial directly compares the two approaches to determine which yields greater improvement in gait and cognitive function in this transitional population.
Why it matters
Potential benefit: If successful, the better-performing program could help slow decline in walking and thinking and potentially delay progression toward dementia in older adults with MCR.
How similar studies have gone: Previous smaller trials suggest exergaming can improve balance and some cognitive measures in older adults, but direct head-to-head comparisons with neuromuscular programs specifically in people with MCR are limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Being over 65 years of age * Having a Barthel Daily Living Activities Index score of ≥ 90 * Having a Mini Mental Status Score (MMSE) of ≥24 * Having the ability to walk with or without a walking aid * Having a slow walking speed * Having subjective memory complaints Exclusion Criteria: * Presence of Dementia * Major Depression * Generalized Anxiety Disorder and Delirium * Parkinson's Disease * Anemia * Thyroid Disease * Vitamin B12 Deficiency * Malnutrition * Terminal Illness * Hearing or Visual Impairment
Where it's running
-
Balıkesir Üniversitesi
Balıkesir, Turkey (Türkiye) Recruiting
Study contacts
- Principal investigator: Gulfidan TOKGÖZ, Lecturer, PhD (c) — İstanbul University-Cerrahpasa
- Study coordinator: GULFİDAN TOKGÖZ, Lecturer, PhD (c)
- Email: gulfidan.tokgoz@gmail.com
- Phone: +90552 022 76 32
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.