Exergaming versus neuromuscular exercise for older adults with Motoric Cognitive Risk

Effect of Exergaming Program Versus Neuromuscular Exercise on Locomotor and Cognitive Functions in Elderly People With Motor Cognitive Risk Syndrome

Not applicable Interventional Istanbul University - Cerrahpasa · NCT07045259

This trial will test whether a video-game-based exercise program (exergaming) or a traditional neuromuscular exercise program better improves walking and thinking in people aged 65 and older with Motoric Cognitive Risk Syndrome.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment60 (estimated)
Ages65 Years and up
SexAll
SponsorIstanbul University - Cerrahpasa Academic / other
Locations1 site (Balıkesir)
Trial IDNCT07045259 on ClinicalTrials.gov

What this trial studies

Older adults meeting criteria for Motoric Cognitive Risk (slow gait plus subjective memory complaints, preserved basic function and MMSE ≥24) will be assigned to either a structured neuromuscular exercise program or a supervised exergaming exercise program delivered by trained staff. Both interventions involve regular, supervised training sessions over a defined intervention period, with baseline and post-intervention assessments. Primary outcomes include locomotor measures such as gait speed and mobility tests and cognitive measures such as global cognition and memory tests. The trial directly compares the two approaches to determine which yields greater improvement in gait and cognitive function in this transitional population.

Who should consider this trial

Good fit: Ideal candidates are ambulatory people aged 65 or older with subjective memory complaints, slow walking speed, preserved basic daily function (Barthel ≥90), and MMSE ≥24.

Not a fit: Patients with dementia, major depression, Parkinson's disease, significant sensory impairments, or medical conditions such as anemia, thyroid disease, vitamin B12 deficiency, malnutrition, or terminal illness are unlikely to qualify or benefit.

Why it matters

Potential benefit: If successful, the better-performing program could help slow decline in walking and thinking and potentially delay progression toward dementia in older adults with MCR.

How similar studies have performed: Previous smaller trials suggest exergaming can improve balance and some cognitive measures in older adults, but direct head-to-head comparisons with neuromuscular programs specifically in people with MCR are limited.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Being over 65 years of age
* Having a Barthel Daily Living Activities Index score of ≥ 90
* Having a Mini Mental Status Score (MMSE) of ≥24
* Having the ability to walk with or without a walking aid
* Having a slow walking speed
* Having subjective memory complaints

Exclusion Criteria:

* Presence of Dementia
* Major Depression
* Generalized Anxiety Disorder and Delirium
* Parkinson's Disease
* Anemia
* Thyroid Disease
* Vitamin B12 Deficiency
* Malnutrition
* Terminal Illness
* Hearing or Visual Impairment

Where this trial is running

Balıkesir

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Motoric Cognitive Risk SyndromeElderlyGeriatric PatientExergamingNeuromuscular Exerciseneuromuscular exerciseexergaming
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.