Exercises to help older women with urinary incontinence and reduce falls
MoVE on Up: Mobility and Voiding Exercises in Older Women with Urinary Incontinence
This study is testing whether a special exercise program can help older women with urinary incontinence reduce their risk of falling and improve their mobility.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 375 (estimated) |
| Ages | 70 Years and up |
| Sex | Female |
| Sponsor | University of Pennsylvania Academic / other |
| Locations | 1 site (Philadelphia, Pennsylvania) |
| Trial ID | NCT05375344 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates a multidimensional intervention aimed at reducing falls in older women suffering from urinary urge incontinence. Participants will be randomly assigned to either an exercise group, which includes balance and strength training, bladder training, and home hazard assessments, or a control group that receives informational booklets on fall prevention and behavioral treatment. The study focuses on women aged 70 and older who live independently and have low physical activity levels. The goal is to assess the effectiveness of the exercise intervention in improving mobility and managing urinary incontinence.
Who should consider this trial
Good fit: Ideal candidates for this study are women aged 70 and older who live independently and experience moderate to severe urge-predominant urinary incontinence.
Not a fit: Patients with pelvic organ prolapse beyond the hymen or those undergoing active cancer treatment may not benefit from this study.
Why it matters
Potential benefit: If successful, this intervention could significantly improve the quality of life for older women by reducing falls and managing urinary incontinence.
How similar studies have performed: Other studies have shown success with similar exercise interventions for managing urinary incontinence and improving mobility in older adults.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Female * 70 or older * Living independently in the community * Willingness to be randomized. * Ability to read and understand English * Be able to provide informed consent * Low physical activity (physically active for 30 minutes or more less than or equal to 2 days per week on average over the past 6 months) per PAS * Ambulatory (defined as patient not confined to bed or wheelchair OR ability to walk with or without an assistive device) * Self-reported moderate to severe urge-predominant UI based on the ICIQ-SF \> 6 (Q 1+2+3) * Not planning to initiate new UI or overactive bladder (OAB) treatment during the study duration * Capable of participation in an exercise program without exacerbating any pre-existing condition(s), as determined by the study PI or designee Exclusion Criteria: * Pelvic organ prolapse passed the hymen (per patient report) * Undergoing active treatment for cancer (other than non-melanoma skin cancer) * Uncorrected visual or hearing loss. * Other urinary conditions or procedures that may affect continence status for example: urethral diverticulum, previous augmentation cystoplasty * Progressive neurodegenerative disease e.g. Parkinson's disease, multiple sclerosis per patient report * History of stroke or carotid sensitivity (i.e. syncopal falls) per patient report * Unstable cardiac disease per patient report * Fracture or joint replacement within the last six months per patient report * Significant cognitive impairment (defined as a modified TICs score of \< 27) * Per PI discretion, participant cannot enroll in study
Where this trial is running
Philadelphia, Pennsylvania
- University of Pennsylvania — Philadelphia, Pennsylvania, United States (Recruiting)
Study contacts
- Principal investigator: Uduak U Andy, MD — University of Pennsylvania
- Study coordinator: Uduak U Andy, MD
- Email: uduakumoh.andy@pennmedicine.upenn.edu
- Phone: (215) 662-7709
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.