Clinical trial Recruiting at 1 site Interventional Ages 18 to 35

Exercise with metronome cues for athletes recovering from ACL surgery

Official title: Terminal Knee Extension Exercise Synchronize With Audible Cues on Motor Unit Behavior of Vastus Medialis Muscle in Athletes With Anterior Cruciate Ligament Reconstruction

Run by Mahidol University · NCT06662955 · Data updated 2026-11-12

This study tests if using a metronome to guide knee exercises can help athletes recovering from ACL surgery improve their muscle control and function.

Quick facts

Study typeInterventional
Ages18 Years to 35 Years
SexAll
Enrollment40 (estimated)
SponsorMahidol University
Academic / other
Locations1 site (Salaya, Changwat Nakhon Pathom)
StatusRecruiting
StartedOctober 20, 2024
Main results expectedOctober 19, 2026
Study endsDecember 30, 2026
Registry record updatedDecember 12, 2025
Trial IDNCT06662955 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are male or female athletes aged 18-35 who have undergone primary ACL reconstruction within the last two weeks and have mild or no resting pain.

Probably not a fit

Patients who are non-weight bearing post-surgery or have hearing impairments that prevent them from synchronizing with the metronome will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of terminal knee extension exercises synchronized with audible metronome cues on neuromuscular control in athletes who have undergone anterior cruciate ligament reconstruction. The focus is on enhancing the activation of the vastus medialis muscle to improve motor unit behavior during rehabilitation. Participants will engage in a single session of this exercise to assess immediate changes in muscle function and control. The study aims to provide insights into how sensory integration techniques can optimize recovery outcomes for athletes post-surgery.

Why it matters

Potential benefit: If successful, this approach could lead to improved rehabilitation outcomes and faster recovery for athletes after ACL reconstruction.

How similar studies have gone: While similar approaches have been explored, this specific integration of audible cues with knee rehabilitation exercises is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Male or female participants who receive primary ACL reconstruction within 2 weeks with or without meniscus repair
* No or mild resting pain (Numeric rating scale ≤ 3)
* Reconstruction procedures using autograft including hamstrings or bone-patella bone grafts
* Age range 18-35 years (33).
* BMI of 18.5-25 kg/m² (34).
* Tegner activity scale ≥ level 4

Exclusion Criteria:

* Non-weight bearing within 2 weeks after the operation (prescription from surgeon)
* Hearing problem, such as being unable to hear the metronome sound or being unable to synchronize exercises with the metronome correctly
* Limitations in knee extension range caused by joint stiffness evaluated by using passive knee range of motion
* Unable to perform active and passive ≥ 30º knee flexion on the operative side
* History of serious injury or operation of lower back and lower extremities such as fracture
* Lower back or lower extremities pain within 6 months before the study
* On the pain killer medication

Where it's running

  • Faculty of Physical Therapy, Mahidol University
    Salaya, Changwat Nakhon Pathom, Thailand
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.