Exercise training program for organ transplant recipients
Effect of an Exercise Training Intervention on Health-related Quality of Life and Psychosocial and Behavioral Variables in Adult Solid Organ Transplant Recipients: a Quasi-experimental Study Design
This study tests whether a special exercise program can help organ transplant recipients feel better and improve their quality of life.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 500 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Sponsor | Universitaire Ziekenhuizen KU Leuven Academic / other |
| Locations | 1 site (Leuven) |
| Trial ID | NCT02533245 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effects of the 'Transplantoux' exercise training intervention on quality of life and patient-reported outcomes in solid organ transplant recipients. Participants will engage in a home-based individualized exercise program and supervised group training sessions over six months, culminating in a climb of Mont Ventoux. The study compares outcomes between transplant recipients participating in the exercise program and a matched control group. The goal is to assess improvements in health-related quality of life, psychosocial factors, and behavioral variables.
Who should consider this trial
Good fit: Ideal candidates include solid organ transplant recipients aged 18 to 70 years who are more than one year post-transplant.
Not a fit: Patients with recent organ rejection, severe co-morbidities, or contraindications for exercise may not benefit from this study.
Why it matters
Potential benefit: If successful, this intervention could significantly enhance the quality of life and overall health outcomes for organ transplant recipients.
How similar studies have performed: Limited research has shown positive outcomes for exercise interventions in transplant populations, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
1. Tx exercise group: Inclusion Criteria: * Tx recipient (heart, lung, liver, kidney, pancreas or small bowel) * Age between 18 - 70 years * More than 1y post-transplant Exclusion Criteria: * Rejection last 6 months * Severe co-morbidity * Contra-indication for severe exercise (e.g. cardiovascular disease) * Insufficient knowledge of Dutch language 2. Tx matched control group Inclusion Criteria: * Tx recipient (heart, lung, liver, kidney, pancreas or small bowel) * Age between 18 - 70 years * More than 1y post-transplant Exclusion Criteria: * Rejection last 6 months * Insufficient knowledge of Dutch language 3. Healthy exercise group: Inclusion Criteria: * Age between 18 - 70 years Exclusion Criteria: * Contra-indication for severe exercise * Insufficient knowledge of Dutch language
Where this trial is running
Leuven
- University Hospitals Leuven — Leuven, Belgium (Recruiting)
Study contacts
- Principal investigator: Diethard Monbaliu, MD, PhD — University Hospital Leuven, Abdominal Transplant Surgery
- Study coordinator: Evi Masschelein, PhD
- Email: evi.masschelein@kuleuven.be
- Phone: +3216372622
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.