Exercise training for patients with atrial fibrillation

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project evaluates the effects of high-intensity interval training (HIIT) versus moderate-intensity continuous exercise training (MICE) and standard care on exercise capacity and quality of life in patients with persistent or permanent atrial fibrillation. The study aims to provide evidence supporting the inclusion of exercise in the management of atrial fibrillation, which is often overlooked in standard care. By comparing different exercise modalities, the research seeks to identify effective interventions that can improve patient outcomes and overall well-being. The findings could lead to new recommendations for cardiac rehabilitation in this patient population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. persistent or permanent atrial fibrillation;
2. rate controlled with a resting ventricular rate of equal to or less than 100 bpm;
3. able to perform a symptom-limited exercise test;
4. at least 40 years of age (i.e. participants must be 40 years or older);

Exclusion Criteria:

1. currently participating in routine exercise training (more than two times per week);
2. unstable angina;
3. diagnosed severe mitral or aortic stenosis;
4. diagnosed hypertrophic obstructive cardiomyopathy with significant obstruction;
5. pregnant, lactating or planning to become pregnant during the study period;
6. unable to provide written, informed consent, or
7. unwilling or unable to return for follow up at week 12.

Where it's running

• London Health Sciences Network
  London, Ontario, Canada Recruiting
• University of Ottawa Heart Insititue
  Ottawa, Ontario, Canada Recruiting

Study contacts

• Principal investigator: Jennifer L Reed, PhD — Ottawa Heart Institute Research Corporation
• Study coordinator: Jennifer L Reed, PhD
• Email: jreed@ottawaheart.ca
• Phone: 613-696-7392

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.