Exercise to Improve Sleep in Parkinson's Disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of three types of exercise—cardiovascular, resistance, and a combination of both—on sleep quality and architecture in individuals with Parkinson's disease. Participants will engage in their assigned exercise regimen or a control condition for 12 weeks, with assessments conducted at the start, after the intervention, and at an 8-week follow-up. The study aims to determine if improvements in sleep are linked to enhancements in quality of life aspects such as cognitive and motor function.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Persons with mild-moderate idiopathic Parkinson's Disease (Modified Hoehn \& Yahr Scale stages 0.5-3.5);
* On a stable dosage of medication during the previous month;
* Having poor sleep quality defined as a score \> 15 in the PDSS-2 and/or reporting subjective sleep complaints affecting their sleep quality;

Exclusion Criteria:

* Having atypical parkinsonism, dementia, stroke, or any other neurological condition;
* Presenting severe untreated obstructive sleep apnea (OSA);
* Having a Montreal Cognitive Assessment (MoCA) score \<18
* Having a Beck Depression Inventory score \>31;
* Having absolute contraindications to exercise;
* Having severe osteoporosis;
* Participating in an exercise or drug trial during the period of the study;
* Exceeding the physical activity levels recommended for the general population (≥150 minutes/week of moderate-intensity or ≥75 minutes/week of vigorous-intensity cardiovascular activity) and/or strengthening activities ≥2 days/week.

Where it's running

• Jewish Rehabilitation Hospital
  Laval, Quebec, Canada Recruiting
• Human Brain Control of Locomotion Laboratory
  Montreal, Quebec, Canada Recruiting
• Cummings Centre
  Montreal, Quebec, Canada Not yet recruiting

Study contacts

• Principal investigator: Marc Roig, Ph.D. — McGill University
• Study coordinator: Marc Roig, Ph.D.
• Email: marc.roigpull@mcgill.ca
• Phone: 514-398-4400

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.