Exercise to Improve Outcomes in Head and Neck Cancer Patients
Can Exercise Ameliorate Immunosenescence and Thereby Reduce Relapse in Head and Neck Cancer Patients
This study is testing if a specific exercise program can help head and neck cancer patients recover better after surgery and possibly lower their chances of cancer coming back.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 180 (estimated) |
| Ages | 20 Years to 80 Years |
| Sex | All |
| Sponsor | Chang Gung Memorial Hospital Academic / other |
| Locations | 1 site (New Taipei City) |
| Trial ID | NCT06851988 on ClinicalTrials.gov |
What this trial studies
This project aims to determine if a safe and effective exercise prescription can help head and neck cancer patients after surgery, particularly focusing on those with oral cancer. The study will explore the relationship between high-intensity interval training (HIIT) and immunosenescence, a condition that may increase cancer recurrence risk. By encouraging regular exercise, the investigators hope to enhance recovery and reduce the likelihood of cancer relapse in these patients. The research will involve monitoring physical activity and assessing its impact on patient outcomes over three years.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 20 and older diagnosed with squamous cell carcinoma who are undergoing concurrent chemoradiotherapy.
Not a fit: Patients with an ECOG performance status of 2 or higher, or those unable to tolerate exercise, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a new approach to improve recovery and reduce cancer recurrence in head and neck cancer patients through exercise.
How similar studies have performed: While exercise interventions have shown success in other cancer populations, the effectiveness in head and neck cancer survivors is still inadequately understood, making this approach somewhat novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age ≥20 2. Pathology:Squamous cell carcinoma 3. Need CCRT treatment 4. ECOG PS\<2 5. Agree with blood drawing, excise training, questionnaire Exclusion Criteria: 1. ECOG PS≥2 2. Unable to tolerate basic exercise, or CCRT treatment 3. Mental illness or any medical illness or concurrent illness that may be aggravated by exercise training or unmanageable 4. Any medical condition that unsuitable for exercise 5. Disagree to trial procedures: exercise, blood draws, questionnaire
Where this trial is running
New Taipei City
- TuCheng Hospital — New Taipei City, Taiwan (Recruiting)
Study contacts
- Study coordinator: Wan-Chin Kuo
- Email: troublefup6@cgmh.org.tw
- Phone: 03-3196200
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.