Exercise programs during hemodialysis to improve function and quality of life
Official title: Physical Exercise in Hemodialysis Patients in End Stage Kidney Disease
Run by Ricerca Nefrocenter · NCT07820514 · Data updated 2026-11-12
This study tests whether aerobic cycling or elastic-band resistance exercise during hemodialysis is safe and helpful for adults on maintenance dialysis.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 312 (estimated) |
| Sponsor | Ricerca Nefrocenter Academic / other |
| Locations | 1 site (Torre del Greco) |
| Status | Recruiting |
| Started | June 1, 2024 |
| Main results expected | October 1, 2025 |
| Study ends | March 1, 2027 |
| Registry record updated | September 15, 2026 |
| Trial ID | NCT07820514 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18 or older on maintenance hemodialysis for more than 3 months who are clinically stable and able to provide informed consent.
✕Probably not a fit
Patients with unstable medical conditions or contraindications to intradialytic exercise may not benefit and may be excluded from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study compares three approaches in adults receiving maintenance hemodialysis: intradialytic aerobic exercise using a cycle ergometer, intradialytic elastic-band resistance exercise, and standard care without added exercise. Participants are randomly or sequentially assigned to one of the three groups and will perform scheduled sessions during dialysis. Outcomes include physical performance, body composition, quality of life, and dialysis-related metrics measured at baseline and after six months. The goal is to determine tolerability and potential benefits of each exercise modality compared with standard care. The trial is led by Ricerca Nefrocenter with collaboration from the University of Naples, Federico II University, and is conducted at NefroCenter Dialysis Centers in Torre del Greco and surrounding locations.
Why it matters
Potential benefit: If successful, patients could experience improved physical function, better body composition, and enhanced quality of life during dialysis.
How similar studies have gone: Previous intradialytic exercise research suggests safety and potential functional benefits, but results vary by modality and population, making this multi-arm trial informative.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥18 years. * Receiving maintenance hemodialysis for more than 3 months. * Clinically stable condition. * Ability and willingness to provide written informed consent. Exclusion Criteria: * Unstable angina. * Uncontrolled hypertension. * Any medical condition judged by the treating nephrologist to contraindicate or make intradialytic exercise unsafe
Where it's running
-
NefroCenter Dialysis Centers
Torre del Greco, Italy Recruiting
Study contacts
- Study coordinator: Ersilia Satta, PhD MD
- Email: e.satta@consorzionefrocenter.it
- Phone: +39 3395703091
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.