Exercise program to improve quality of life in breast cancer patients

Prehabilitation Exercise Program in Breast Cancer: Effects on Quality of Life and Tumor Microenvironment (PEP_BC)

NA · Institut Nacional d'Educacio Fisica de Catalunya · NCT06360809

This study is testing whether a special exercise program can help breast cancer patients feel better and improve their health before surgery and chemotherapy.

Quick facts

PhaseNA
Study typeInterventional
Enrollment76 (estimated)
Ages18 Years to 65 Years
SexFemale
SponsorInstitut Nacional d'Educacio Fisica de Catalunya (other)
Drugs / interventionschemotherapy
Locations1 site (Barcelona)
Trial IDNCT06360809 on ClinicalTrials.gov

What this trial studies

This study focuses on a prehabilitation exercise program designed for patients diagnosed with hormone receptor-positive breast cancer. The program aims to prepare patients both mentally and physically for upcoming clinical and surgical procedures, potentially reducing complications and enhancing the effectiveness of chemotherapy. Researchers will investigate how physical exercise influences the tumor microenvironment and overall quality of life, with the hypothesis that it will lead to improvements in fatigue, muscle mass, and health outcomes. The study will involve patients aged 18 to 65 who meet specific eligibility criteria and have a four-week window between diagnosis and surgery.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 to 65 with hormone receptor-positive breast cancer who can safely participate in physical exercise.

Not a fit: Patients with metastatic breast cancer or those who have engaged in structured physical exercise in the last six months may not benefit from this study.

Why it matters

Potential benefit: If successful, this program could significantly enhance the quality of life and treatment outcomes for breast cancer patients.

How similar studies have performed: Previous studies have shown benefits of preoperative exercise in various cancer types, indicating potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Be aged between 18 and 65 years.
* Have a diagnosis of hormone receptor-positive breast cancer (ER and PR).
* Have no medical contraindications that prevent them from participating in physical exercise.
* Have four weeks period between diagnosis and surgery

Exclusion Criteria:

* Being diagnosed of another primary and/or secondary tumor or being in metastatic stage.
* Presence of uncontrolled serious medical illness
* Presence of any medical, psychological or social problem that could seriously interfere with the patient's participation in the study
* Those who have engaged in structured physical exercise in the last 6 months.

Where this trial is running

Barcelona

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Breast Cancer, breast cancer, physical exercise, tumor microenvironment, oxidative hemodynamics, near-infrared spectroscopy, diffuse correlation optical spectroscopy, prehabilitation therapy

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.