Exercise program for improving health in young adults with Type 1 Diabetes
Targeting Vascular and Skeletal Muscle Health to Improve Quality of Life in Males and Females with Type 1 Diabetes
This study is testing whether a structured exercise program can help young adults with Type 1 Diabetes improve their muscle health and reduce complications related to their condition.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 168 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | McMaster University Academic / other |
| Locations | 1 site (Hamilton, Ontario) |
| Trial ID | NCT05740514 on ClinicalTrials.gov |
What this trial studies
This study aims to explore the effects of a structured exercise program on individuals with Type 1 Diabetes (T1D), focusing on improving muscle health and reducing complications associated with the condition. Participants aged 18-30 or 45-65 who are sedentary or recreationally active will engage in regular exercise, while the study will monitor their health outcomes and muscle metabolism. The research addresses the barriers to exercise faced by those with T1D, such as fear of hypoglycemia and lack of knowledge about effective exercise strategies. By understanding the differential responses to exercise between genders, the study seeks to tailor interventions for better health outcomes.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18-30 or 45-65 who are sedentary or engage in minimal physical activity.
Not a fit: Patients with Type 2 diabetes, prediabetes, or significant health conditions that prevent safe participation in exercise may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved health and reduced complications for individuals with Type 1 Diabetes through effective exercise strategies.
How similar studies have performed: Other studies have shown positive outcomes with exercise interventions in diabetes management, suggesting that this approach is promising.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age of 18-30 or 45-65 * Sedentary or recreationally active, as defined by self-reported activity levels below the recommended 150-minute minimum of moderate-to-vigorous intensity physical activity per week Exclusion Criteria: * Chronic use of anti-inflammatory, glucocorticoid, or other pain-relief medication * History of daily cannabis, tobacco, or nicotine use within six months of study initiation * BMI \>30kg/m2 * Prediabetes * Type 2 diabetes * Health conditions that put the subject at risk to participate in exercise during this study * Atypical or Grade 2b diabetic sensorimotor polyneuropathy * More than one lifetime event of hospitalization for diabetic ketoacidosis
Where this trial is running
Hamilton, Ontario
- McMaster University — Hamilton, Ontario, Canada (Recruiting)
Study contacts
- Principal investigator: Thomas J Hawke, PhD — McMaster University
- Study coordinator: Thomas J Hawke, PhD
- Email: hawke@mcmaster.ca
- Phone: 905-525-9140
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.