Exercise program for improving health in young adults with Type 1 Diabetes
Official title: Targeting Vascular and Skeletal Muscle Health to Improve Quality of Life in Males and Females with Type 1 Diabetes
Run by McMaster University · NCT05740514 · Data updated 2026-11-12
This study is testing whether a structured exercise program can help young adults with Type 1 Diabetes improve their muscle health and reduce complications related to their condition.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 168 (estimated) |
| Sponsor | McMaster University Academic / other |
| Locations | 1 site (Hamilton, Ontario) |
| Status | Recruiting |
| Started | October 1, 2023 |
| Main results expected | November 2027 |
| Study ends | November 2027 |
| Registry record updated | December 5, 2024 |
| Trial ID | NCT05740514 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18-30 or 45-65 who are sedentary or engage in minimal physical activity.
✕Probably not a fit
Patients with Type 2 diabetes, prediabetes, or significant health conditions that prevent safe participation in exercise may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to explore the effects of a structured exercise program on individuals with Type 1 Diabetes (T1D), focusing on improving muscle health and reducing complications associated with the condition. Participants aged 18-30 or 45-65 who are sedentary or recreationally active will engage in regular exercise, while the study will monitor their health outcomes and muscle metabolism. The research addresses the barriers to exercise faced by those with T1D, such as fear of hypoglycemia and lack of knowledge about effective exercise strategies. By understanding the differential responses to exercise between genders, the study seeks to tailor interventions for better health outcomes.
Why it matters
Potential benefit: If successful, this study could lead to improved health and reduced complications for individuals with Type 1 Diabetes through effective exercise strategies.
How similar studies have gone: Other studies have shown positive outcomes with exercise interventions in diabetes management, suggesting that this approach is promising.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age of 18-30 or 45-65 * Sedentary or recreationally active, as defined by self-reported activity levels below the recommended 150-minute minimum of moderate-to-vigorous intensity physical activity per week Exclusion Criteria: * Chronic use of anti-inflammatory, glucocorticoid, or other pain-relief medication * History of daily cannabis, tobacco, or nicotine use within six months of study initiation * BMI \>30kg/m2 * Prediabetes * Type 2 diabetes * Health conditions that put the subject at risk to participate in exercise during this study * Atypical or Grade 2b diabetic sensorimotor polyneuropathy * More than one lifetime event of hospitalization for diabetic ketoacidosis
Where it's running
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McMaster University
Hamilton, Ontario, Canada Recruiting
Study contacts
- Principal investigator: Thomas J Hawke, PhD — McMaster University
- Study coordinator: Thomas J Hawke, PhD
- Email: hawke@mcmaster.ca
- Phone: 905-525-9140
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Predictive CGM with App for people with type 1 or insulin-treated type 2 diabetes
This study tests whether using the Accu-Chek SmartGuide CGM with its Predict App can reduce fear of hypoglycemia and improve related behaviors and confidence in adults with type 1 or insulin-treated type 2 diabetes.
-
Tirzepatide for type 1 diabetes patients who are overweight or obese
This study tests whether tirzepatide can affect stomach emptying in adults with type 1 diabetes and overweight or obesity.
-
Oral insulin vs. subcutaneous insulin in adults with type 1 diabetes
This study tests an oral insulin tablet (SCD0503) against subcutaneous insulin and placebo to see how it behaves in the blood and helps control blood sugar in adults with type 1 diabetes.
-
Genetic risk score and progression to insulin in type 1 diabetes
This study tests whether a genetic risk score can predict which people with type 1 diabetes will need insulin progression over three years.
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Home-based use of an advanced hybrid closed-loop insulin pump with telemonitoring for adults with type 1 diabetes
This study tests whether starting an advanced hybrid closed-loop insulin pump at home, with online education and telemonitoring, is feasible and safe for adults with type 1 diabetes.
-
Diabetes multimorbidity and a voice diary app to help self-manage
This study tests whether the Fabla-diabetesMM audio diary app is feasible and helpful for older adults with type 1 or type 2 diabetes who also have additional chronic conditions.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.