Exercise program for children and adolescents after cancer treatment
Official title: Effects of a Physical Activity Program On Cardiorespiratory Fitness in Children and Adolescents folloWing Acute cancER Treatment: a Randomized Controlled Trial
Run by Universität Duisburg-Essen · NCT04765020 · Data updated 2026-11-12
This study is testing if a 12-week exercise program can help children and teens feel stronger and healthier after finishing cancer treatment.
Quick facts
| Phase | Phase2; Phase3 |
|---|---|
| Study type | Interventional |
| Ages | 7 Years to 23 Years |
| Sex | All |
| Enrollment | 56 (estimated) |
| Sponsor | Universität Duisburg-Essen Academic / other |
| Locations | 1 site (Krefeld) |
| Status | Recruiting |
| Started | June 21, 2021 |
| Main results expected | December 2027 |
| Study ends | June 2028 |
| Registry record updated | May 15, 2026 |
| Trial ID | NCT04765020 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are children and adolescents aged 7 to 23 who have completed acute cancer treatment and are receiving follow-up care.
✕Probably not a fit
Patients under 7 or over 23 years of age, or those with medical conditions that limit their ability to participate, may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The POWER study is a two-arm exercise intervention designed for pediatric patients who have recently completed acute cancer treatment. It aims to assess the impact of a 12-week moderate to high-intensity exercise program on cardiorespiratory fitness in children and adolescents, starting six weeks post-treatment. Participants will be randomly assigned to either an intervention group, which receives supervised exercise sessions and personalized activity targets, or a control group that receives general exercise recommendations. The study will also evaluate additional performance markers and patient-reported outcomes related to quality of life and health.
Why it matters
Potential benefit: If successful, this program could significantly improve cardiorespiratory fitness and overall health outcomes for children and adolescents recovering from cancer.
How similar studies have gone: Other studies have shown positive outcomes with exercise interventions in pediatric oncology, suggesting this approach is promising.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Children and adolescents between 7 and 23 years of age * Completion of acute cancer treatment and receiving follow-up care in Krefeld (Helios Hospital Krefeld) * 6 weeks post cancer-treatment * Signed informed consent (Parents and Patient) Exclusion Criteria: * \<7 years of age, \>23 years of age * Medical condition that limits participation in one of the study arms * Inability to follow the training-protocol * Inability to carry out the spiroergometry on a cycle ergometer
Where it's running
-
Helios Klinik Krefeld
Krefeld, Germany Recruiting
Study contacts
- Principal investigator: Miriam Götte, Phd — University Hospital, Essen
- Study coordinator: Sandra Goertz, B.Sc.
- Email: sandra.goertz@helios-gesundheit.de
- Phone: +49 2151 32 45098
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.