Exercise capacity, muscle oxygenation, and aortic stiffness after mitral valve intervention

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a single-center observational comparison of adults (18–80) who underwent mitral valve intervention at least three months earlier and age-matched healthy controls. Participants will undergo cardiopulmonary exercise testing to measure exercise capacity, noninvasive measures of aortic stiffness (such as pulse wave velocity), and muscle oxygenation monitoring during activity. The study excludes patients with recent infection, other valve interventions, or conditions that limit functional capacity, and excludes controls with chronic disease or heavy smoking history. Findings will be used to characterize persistent physiologic limitations after mitral valve intervention and inform rehabilitation strategies.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Patients;

* Between the ages of 18-80
* Patients who have undergone mitral valve intervention due to mitral stenosis
* At least 3 months have passed since the intervention

Healthy controls;

* Between the ages of 18 and 80
* Agreeing to participate voluntarily in the study

Exclusion Criteria:

Patients;

* Patients who have undergone aortic valve intervention other than mitral valve intervention
* Acute infection
* Orthopedic, neurological or psychological disorders that will affect functional capacity

Healthy Controls;

* diagnosed chronic disease,
* acute infection
* A smoking history of at least 10 packs×years or more

Where it's running

• Gazi University Faculty of Health Sciences Department of Physiotherapy and Rehabilitation, Cardiopulmonary Rehabilitation Unit
  Ankara, Çankaya, Turkey (Türkiye) Recruiting

Study contacts

• Principal investigator: Özden SEÇKİN GÖBÜT, Dr — Gazi University
• Study coordinator: Meral BOŞNAK GÜÇLÜ, Prof. Dr.
• Email: meralbosnak@gazi.edu.tr
• Phone: +90(312)2162647

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.