Examining Ventilation Quality During CPR for Out-of-Hospital Cardiac Arrest
CAvent-Ventilation During Advanced Cardiopulmonary Resuscitation in Out-of-hospital Cardiac Arrest- a Descriptive Study
This study is trying to see how well emergency responders are providing breaths during CPR for people who have had a cardiac arrest outside of the hospital.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 200 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Uppsala University Academic / other |
| Locations | 2 sites (Amersfoort, Utrecht and 1 other locations) |
| Trial ID | NCT04237727 on ClinicalTrials.gov |
What this trial studies
This multicenter observational study aims to assess the quality of ventilation provided by Emergency Medical Service (EMS) personnel during cardiopulmonary resuscitation (CPR) for out-of-hospital cardiac arrest (OHCA) patients. The study will measure ventilation frequency, tidal volume, and minute ventilation during CPR, utilizing both supraglottic devices and endotracheal intubation. Data will be collected from at least 200 patients over a two-year period at two sites in Sweden and the Netherlands, with additional outcomes related to return of spontaneous circulation (ROSC) and neurological status evaluated at 30 days and 6 months post-event.
Who should consider this trial
Good fit: Ideal candidates for this study are adults experiencing out-of-hospital cardiac arrest who are treated with CPR by EMS personnel.
Not a fit: Patients under 18 years of age, those who are pregnant, or individuals with trauma-related cardiac arrest will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the quality of ventilation during CPR, potentially improving survival rates and neurological outcomes for patients experiencing out-of-hospital cardiac arrest.
How similar studies have performed: Previous studies have explored ventilation techniques during CPR, but this specific approach focusing on ventilation quality in OHCA patients is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Out-of-hospital cardiac arrest (OHCA) treated with CPR performed by the EMS personnel Exclusion Criteria: * Patient age \< 18 years * Known pregnancy * Trauma related cardiac arrest (inc. hanging)
Where this trial is running
Amersfoort, Utrecht and 1 other locations
- Regionale Ambulance Voorziening Utrecht, Netherlands — Amersfoort, Utrecht, Netherlands (Recruiting)
- Uppsala University hospital — Uppsala, Sweden (Recruiting)
Study contacts
- Principal investigator: Sten Rubertsson, PhD — Uppsala University department of surgical sciences
- Study coordinator: Sten Rubertsson, PhD
- Email: sten.rubertsson@surgsci.uu.se
- Phone: +46708693996
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.