Examining treatment variations for cholecystitis in the Netherlands
Variation in Cholecystitis Treatment and Outcome in the Netherlands; a Nation-wide Cohort Study
This study looks at how different hospitals in the Netherlands treat cholecystitis to see if those differences affect how well patients do and how long they stay in the hospital.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 3000 (estimated) |
| Ages | 18 Years to 120 Years |
| Sex | All |
| Sponsor | St. Antonius Hospital Academic / other |
| Locations | 1 site (Nieuwegein, Utrecht) |
| Trial ID | NCT06349863 on ClinicalTrials.gov |
What this trial studies
This observational study aims to investigate the differences in treatment approaches for cholecystitis across various hospitals in the Netherlands and how these variations affect patient outcomes. It will involve a nationwide cohort of patients diagnosed with cholecystitis over a six-month period, focusing on adherence to treatment guidelines and its impact on hospital stay and complications. The study will also explore factors influencing guideline compliance and identify optimal treatment strategies for different scenarios related to cholecystitis.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 years diagnosed with calculous cholecystitis as the primary reason for hospital admission.
Not a fit: Patients with non-calculous cholecystitis or those under 18 years old may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment protocols for cholecystitis, enhancing patient outcomes and reducing hospital stays.
How similar studies have performed: Other studies have shown variations in treatment approaches can significantly impact outcomes, suggesting this study's findings could be valuable.
Eligibility criteria
Show full inclusion / exclusion criteria
All patients \>18 years with a calculous cholecystitis as primary reason for their hospital admittance. Location of diagnosis may the emergency department, the ward during admittance for diagnostics, or during diagnostic laparoscopy. Cholecystitis is defined according to the TG18 diagnostic criteria for a definitive diagnosis of cholecystitis: A. Local signs of inflammation (Murphy's sign and or RUQ mass/pain/tenderness) + B. Systemic signs of inflammation (Fever, elevated CRP and/or elevated WBC count) + C. Imaging findings characteristic of acute cholecystitis. Patients with a suspected diagnosis (one item in A + one item in B + C), of which the diagnosis is confirmed by peroperative findings, are also included. Patients will be identified by a local study investigator, e.g. a surgeon or surgeon in training.
Where this trial is running
Nieuwegein, Utrecht
- Heelkunde — Nieuwegein, Utrecht, Netherlands (Recruiting)
Study contacts
- Study coordinator: Teus Weijs
- Email: t.j.weijs@gmail.com
- Phone: 0031612093752
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.