Examining the tissue characteristics of cesarean scar niches
Immunohistopathologic Findings of Cesarean Scar Niche
NA · Sohag University · NCT06466343
This study is trying to understand the tissue changes in cesarean scars of women who aren't pregnant to help doctors improve their repair methods.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 18 Years to 45 Years |
| Sex | Female |
| Sponsor | Sohag University (other) |
| Locations | 1 site (Sohag) |
| Trial ID | NCT06466343 on ClinicalTrials.gov |
What this trial studies
This study investigates the histopathologic findings of cesarean scar niches in non-pregnant women who have undergone hysteroscopic repair. It aims to identify the causes of local thinning of the uterine scar after cesarean section and to provide gynecologists with insights regarding the efficacy of their corrective procedures. Patients will be recruited from the Obstetrics and Gynecology outpatient clinic, where their uterine scar niches will be diagnosed using transvaginal ultrasound. The study will collect clinical data and perform hysteroscopic resection followed by histopathological examination of the specimens.
Who should consider this trial
Good fit: Ideal candidates are non-pregnant women with a history of one or more cesarean sections and diagnosed with a cesarean scar defect.
Not a fit: Patients with pelvic inflammatory disease, suspected gynecological malignancies, or other significant health issues such as heart or liver disease may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the understanding of cesarean scar niches and improve treatment outcomes for women experiencing related symptoms.
How similar studies have performed: While there is limited literature on the histopathologic characteristics of cesarean scar niches, similar studies have shown promise in understanding and treating related conditions.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Any Women with history of previous CS once or more with period more than one year from the last CS and had CS scar defect diagnosed by TVUS. Exclusion Criteria: * All women diagnosed with pelvic inflammatory disease, suspected with gynecological malignancy, postmenopausal women, women with heart disease, liver disease, renal impairment or bleeding tendency will be excluded from the study.
Where this trial is running
Sohag
- Sohag University Hospitals — Sohag, Egypt (RECRUITING)
Study contacts
- Principal investigator: mohamed Ab Galal, A.lecturer — sohag faculty of medicine sohag university
- Study coordinator: mohamed Ab Galal, A.Lecturer
- Email: mohamed_hussien1@med.sohag.edu.eg
- Phone: 01095926603
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Cesarean Scar Niche, cesarean scar, Niche