Examining the relationship between Sintilimab levels and treatment outcomes in advanced gastric cancer patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate how the blood concentration of Sintilimab, an immune checkpoint inhibitor, correlates with treatment efficacy and adverse reactions in patients diagnosed with advanced gastric cancer. The study focuses on identifying effective biomarkers that can predict patient responses to Sintilimab, addressing the current lack of pharmacokinetic and pharmacodynamic data in the Chinese population. By analyzing these correlations, the research seeks to provide clinical insights for personalized treatment strategies in gastric cancer management.

Why it matters

Who can join: the full rules

Inclusion Criteria:

A. Patients who were diagnosed with gastric adenocarcinoma or gastroesophageal junction adenocarcinoma; B. Patients who plan to be treated with Sintilimab; C.ECOG score of 0-2; D. Expected survival ≥3 months; E. The patient who have good compliance, follow-up, and can cooperate with relevant treatment and examination; F. Agree to participate in the study and sign the informed consent

Exclusion Criteria:

A. Patients who clinical information and data are incomplete; B. Patients who treated with immune checkpoint inhibitors within 6 months

Where it's running

• Zhongda Hospital Affiliated to Southeast University
  Nanjing, Jiangsu, China Recruiting

Study contacts

• Study coordinator: Lin Liu
• Email: 101012478@seu.edu.cn
• Phone: +86 13913968688

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.