Examining the link between urine proteins and urinary symptoms in men with prostate enlargement

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the relationship between urine levels of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) with lower urinary system parameters in men suffering from benign prostatic hyperplasia (BPH) and associated bladder outlet obstruction. It aims to understand how these proteins correlate with symptoms such as increased urination frequency and difficulty in urination. The intervention involves holmium laser enucleation of the prostate to alleviate symptoms and assess changes in urinary parameters post-procedure. The study focuses on older men, as BPH is a prevalent condition in this demographic.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. 50-80 years Male
2. Patients with bladder outlet obstruction secondary to benign prostate hyperplasia

Exclusion Criteria:

1. Known neurological disease
2. Diabetes
3. Urinary tract infection
4. Previous prostate surgery
5. Spinal Cord Trauma

7-Bladder stone 8-Cerebrovascular disease 9-Chronic Renal Failure 10-Ureteral stenosis

Where it's running

• Marmara University Hospital
  Istanbul, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Haydar Kamil ÇAM, Prof. Dr.
• Email: kamilcam@hotmail.com
• Phone: +905323259547

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Fetal cystoscopy to unblock severe bladder outlet obstruction before birth

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• Tamsulosin alone vs. tamsulosin with tadalafil for troublesome urinary symptoms from enlarged prostate

  This study tests whether adding tadalafil to tamsulosin helps men with BPH see better urinary symptoms and quality of life, using two tadalafil doses over 12 weeks.

  Recruiting Ain Shams University · Cairo, Cairo Governorate · NCT07722884

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.