Examining the link between sleep duration and heart health

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates how different sleep durations affect cardiovascular health, physical activity, and sleep quality by comparing short sleepers (≤ 6 hrs), long sleepers (≥ 9 hrs), and average sleepers (7-8 hrs). Participants will use at-home devices to measure their sleep, physical activity, and blood pressure before attending an in-lab visit for vascular function and blood marker assessments. An optional intervention will encourage participants to maintain an 8-hour sleep schedule for one week, followed by a second in-lab visit to reassess their health metrics.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Men and women ages 25-65y
* Lean and overweight (BMI 18.5-40 kg/m2)
* No acute, chronic, or debilitating medical conditions
* No prescription/non-prescription medications or drugs of abuse
* Current non-smoker (tobacco and marijuana)
* Persons who fit all the above criteria and are suitable based on a medical history and health habits questionnaire, and additional sleep and health profiling questionnaires may be eligible to participate.

Exclusion Criteria:

* Persons with any acute, chronic, or debilitating medical condition except pre-hypertension will be excluded.
* Persons with any symptoms of acute or active illness (e.g. fever, leukocytosis) will be excluded.
* Persons with a history of severe psychiatric illness or psychiatric disorders will be excluded.
* Persons with a history of regular night/or rotating shift work in the past year, or who have traveled more than three time zones during the one month prior to the study will be excluded.
* Pregnant women, decisionally impaired adults, and prisoners will be excluded.

Where it's running

• Oregon Health and Science University
  Portland, Oregon, United States Recruiting

Study contacts

• Principal investigator: Saurabh S Thosar, PhD — Oregon Health and Science University
• Study coordinator: Nicole Chaudhary, MPH
• Email: burkeni@ohsu.edu
• Phone: 5034942064

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.