Examining the link between sleep duration and heart health
Sleep Duration and Cardiovascular Health
This study is testing how different amounts of sleep affect heart health and activity levels in people who sleep less, more, or just the right amount.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 24 (estimated) |
| Ages | 25 Years to 65 Years |
| Sex | All |
| Sponsor | Oregon Health and Science University Academic / other |
| Locations | 1 site (Portland, Oregon) |
| Trial ID | NCT04804124 on ClinicalTrials.gov |
What this trial studies
This study investigates how different sleep durations affect cardiovascular health, physical activity, and sleep quality by comparing short sleepers (≤ 6 hrs), long sleepers (≥ 9 hrs), and average sleepers (7-8 hrs). Participants will use at-home devices to measure their sleep, physical activity, and blood pressure before attending an in-lab visit for vascular function and blood marker assessments. An optional intervention will encourage participants to maintain an 8-hour sleep schedule for one week, followed by a second in-lab visit to reassess their health metrics.
Who should consider this trial
Good fit: Ideal candidates are men and women aged 25-65 who are lean or overweight and have no significant medical conditions.
Not a fit: Patients with acute or chronic medical conditions, severe psychiatric disorders, or those who have recently changed their work schedule may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved cardiovascular health through better sleep management.
How similar studies have performed: Other studies have shown a correlation between sleep duration and cardiovascular health, suggesting this approach has potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Men and women ages 25-65y * Lean and overweight (BMI 18.5-40 kg/m2) * No acute, chronic, or debilitating medical conditions * No prescription/non-prescription medications or drugs of abuse * Current non-smoker (tobacco and marijuana) * Persons who fit all the above criteria and are suitable based on a medical history and health habits questionnaire, and additional sleep and health profiling questionnaires may be eligible to participate. Exclusion Criteria: * Persons with any acute, chronic, or debilitating medical condition except pre-hypertension will be excluded. * Persons with any symptoms of acute or active illness (e.g. fever, leukocytosis) will be excluded. * Persons with a history of severe psychiatric illness or psychiatric disorders will be excluded. * Persons with a history of regular night/or rotating shift work in the past year, or who have traveled more than three time zones during the one month prior to the study will be excluded. * Pregnant women, decisionally impaired adults, and prisoners will be excluded.
Where this trial is running
Portland, Oregon
- Oregon Health and Science University — Portland, Oregon, United States (Recruiting)
Study contacts
- Principal investigator: Saurabh S Thosar, PhD — Oregon Health and Science University
- Study coordinator: Nicole Chaudhary, MPH
- Email: burkeni@ohsu.edu
- Phone: 5034942064
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.